Molecular Horizons - formerly the Centre for Medical and Molecular Bioscience (CMMB) - brings together a multidisciplinary team of chemists and biologists with a common interest in the molecular basis of disease and disease prevention from the School of Chemistry and School of Biological Sciences at the University of Wollongong.

Follow

Papers from 2007

PDF

The importance of slime: does living in a community matrix save algal cells from the toxic effects of copper?, Jacqueline Levy, Dianne F. Jolley, and Jenny L. Stauber

PDF

Sensitivity of marine microalgae to copper: The effect of biotic factors on copper adsorption and toxicity, Jacqueline Levy, Jenny L. Stauber, and Dianne F. Jolley

PDF

Free fatty acids from the crude hexane extract of the aerial parts of Heliotropium indicum Linn. Growing in Phitsanulok, Thailand, Theeraphan Machan, Jurgen Korth, Boonsom Liawruangrath, Saisunee Liawruangrath, Apiwat Baramee, and Stephen G. Pyne

Gene expression and tagging of Streptococcal proteins, Jason D. McArthur, Mark J. Walker, Marie Ranson, Martina L. Sanderson-Smith, Jason N. Cole, Anna Henningham, Amanda J. Cork, and F conlan

Effects of valproic acid on endogenous neural stem/progenitor cells after spinal cord injury in rats, Guoxin Nan, Weihong Liao, Hongyun Li, Yamin Wu, Xu Wang, Li Wang, and Zaiyun Long

PDF

Air-drying of banana: Influence of experimental parameters, slab thickness, banana maturity and harvesting season, Minh-Hue Nguyen and William E. Price

PDF

Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol, P Nizard, Suzanne Tetley, Y Le Drean, T Watrin, P Le Goff, Mark R. Wilson, and Denis Michel

Chromatin crosstalk in development and disease: lessons from REST, Lezanne Ooi and Ian Wood

Electrocoagulation in aqueous alcoholic solutions, Stephen G. Pyne, Duang Buddhasukh, Weerachai Phutdhawong, M Garson, S Chowwanapoonpohn, and K Jumpathong

PDF

The pyrido[1,2-a]azepine Stemona alkaloids, Stephen G. Pyne, Alison T. Ung, Araya Jatisatienr, and Pitchaya Mungkornasawakul

PDF

Crystallization and diffraction data of 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase: a cofactor-free oxygenase of the alpha/beta-hydrolase family, Ruhu Qi, Susanne Fetzner, and Aaron J. Oakley

Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils, Stephen F. Ralph, Janice Aldrich-Wright, Nial J. Wheate, J G. Collins, V J. Higgins, S Kemp, S Wang, and A I. Day

An expanded cavity hexaamine cage for copper(II), Stephen F. Ralph, Paul V. Bernhardt, Richard Bramley, Alan M. Sargeson, and Rodney J. Geue

Platinum recovery using inherently conducting polymers and common fabrics, Stephen F. Ralph, Roza Dimeska, Gordon G. Wallace, and Shannon Little

Octahedral and trigonal prismatic structure preferences in a bicyclic hexaamine cage for zinc(II), cadmium(II) and mercury(II) ions, Stephen F. Ralph, Anthony C. Willis, Alan M. Sargeson, Rodney J. Geue, and Alexia M T Bygott

Synthesis of meso-Extended Tetraaryl Porphyrins, Christopher Richardson and Christopher Reed

An improved synthesis of 2-(1,2,4-thiadiazol-5-yl)pyridine by interception of an intermediate involved in a competing cyclisation reaction., Christopher Richardson and Peter Steel

The first metal complexes of 3,3'-bi-1,2,4-oxadiazole: a curiously ignored ligand, Christopher Richardson and Peter Steel

PDF

The Plasminogen-Binding Group A Streptococcal M Protein-Related Protein Prp Binds Plasminogen via Arginine and Histidine Residues, Martina L. Sanderson-Smith, M. Dowton, Marie Ranson, and Mark J. Walker

N-glycolisation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins, Danielle Skropeta, Daniel J. Rader, Weijun Jin, Monica R. McMahon, Kate Shearston, Philip J. Barter, Kristine C. McGrath, Kerry-Anne Rye, Chatri Settasatian, and Daniela Caiazza

Domino pericyclic reactions of acyclic conjugated (E,Z,E,E)-tetraenes, Danielle Skropeta and Rodney W. Rickards

Effects of glycosylation on the structure and function of the extracellular chaperone clusterin, Elise M. Stewart, Andrew Aquilina, Simon B Easterbrook-Smith, D Murphy-Durland, C Jacobsen, S Moestrup, and Mark R. Wilson

PDF

Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit, Xun-Cheng Su, Slobodan Jergic, Max A Keniry, Nicholas E. Dixon, and Gottfried Otting

Measurement of dissociation constants of high-molecular weight protein-protein complexes by transferred 15N-relaxation, Xun Cheng Su, Slobodan Jergic, Kiyoshi Ozawa, Nicolas Dale Burns, Nicholas E. Dixon, and Gottfried Otting

PDF

Synthesis of benzo[c]chromen-6-ones via novel cyclic aryl-Pd(II)-ester enolate intermediates, Stephen R. Taylor, Alison T. Ung, and Stephen G. Pyne

PDF

The synthesis of 2',2'-bis-benzylisoquinolines and their cytostatic activities, Stephen R. Taylor, Alison T. Ung, and Stephen G. Pyne

PDF

Intramolecular versus intermolecular oxidative couplings of ester tethered di-aryl ethers, Stephen R. Taylor, Alison T. Ung, Stephen G. Pyne, Brian W. Skelton, and Allan H. White

PDF

Elucidation of Double Bond Position in Unsaturated Lipids by Ozone Electrospray Ionization Mass Spectrometry (OzESI-MS), M. C. Thomas, Todd Mitchell, J. M. Deeley, D. G. Harman, R. C. Murphy, and Stephen J. Blanksby

Protein-bound and free UV filters in cataract lenses. The concentration of UV filters is much lower than in normal lenses, Roger J. Truscott, Andrew Aquilina, and Anastasia Korlimbinis

Protein-bound UV filters in normal human lenses: the concentration of bound UV filters equals that of free UV filters in the centre of older lenses, Roger J. Truscott, Andrew Aquilina, and Anastasia Korlimbinis

Gadolinium triflate catalyzed alkylation of pyrroles: efficient synthesis of 3-oxo-2,3-dihydro-1H-pyrrolizine derivatives, Canan Unaleroglu and Arife Yazici

PDF

DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection, Mark J. Walker, A. Hollands, Martina L. Sanderson-Smith, J. N. Cole, J. K. Kirk, A. Henningham, Jason D. McArthur, K. Dinkla, R. K. Aziz, R. G. Kansal, A. J. Simpson, J. T. Buchanan, G. S. Chhatwal, M. Kotb, and V. Nizet

PDF

Effect of protein stabilization on charge state distribution in positive- and negative ion electrospray ionization mass spectra, Stephen J. Watt, Margaret Sheil, Jennifer L. Beck, Pavel Prosselkov, Gottfried Otting, and Nicholas E. Dixon

Multiple oligomeric forms of Escherichia coli DnaB helicase revealed by electrospray ionisation mass spectrometry, Stephen J. Watt, Thitima Urathamakul, Patrick M. Schaeffer, Neal K. Williams, Margaret Sheil, Nicholas E. Dixon, and Jennifer L. Beck

PDF

Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity, Mark R. Wilson, Justin J. Yerbury, and Stephen Poon

The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species, Mark R. Wilson, Justin J. Yerbury, Stephen Poon, Christopher Dobson, C V Robinson, Elise M. Stewart, Janet R. Kumita, Mireille Dumoulin, Gemma L. Caddy, and Christine L. Hagan

Molecular dynamics simulation of human interleukin-4: comparison with NMR data and effect of pH, counterions and force field on tertiary structure stability, Mortiz Winger, Haibo Yu, Christina Redfield, and Wilfred F. van Gunsteren

Cell-free transcription/translation from PCR-amplified DNA for high-throughput NMR studies, Peter S.C. Wu, Kiyoshi Ozawa, Siew P. Lim, Subhash G. Vasudevan, Nicholas E. Dixon, and Gottfried Otting

Extension of the self-consistent-charge density-functional tight-binding method: third-order expansion of the density functional theory total energy and introduction of a modified effective coulomb interaction, Yang Yang, Haibo Yu, Darrin York, Qiang Cui, and Marcus Elstner

The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with pre-fibrillar structures, Justin J. Yerbury, Stephen Poon, Sarah Meehan, Brianna Thompson, Janet R. Kumita, Christopher Dobson, and Mark R. Wilson

PDF

Syntheses of spiro[cyclopropane-1,3'-oxindole]-2-carboxylic acid and cyclopropa[c]quinoline-7b-carboxylic acid and their derivatives, Sarah Yong, Alison T. Ung, Stephen G. Pyne, Brian W. Skelton, and Allan H. White

PDF

Synthesis of novel 3'-spirocyclic-oxindole derivatives and assessment of their cytostatic activities, Sarah Yong, Alison T. Ung, Stephen G. Pyne, Brian W. Skelton, and Allan H. White

PDF

The vibrational spectra of protonated water clusters: A benchmark for self-consistent-charge density-functional tight binding, Haibo Yu and Qiang Cui

PDF

Mechanochemical coupling in the myosin motor domain. II. Analysis of critical residues, Haibo Yu, Liang Ma, Yang Yang, and Qiang Cui

PDF

Mechanochemical coupling in the myosin motor domain. I. Insights from equilibrium active-site simulations, Haibo Yu, Liang Ma, Yang Yang, and Qiang Cui

The characteristics of rhizosphere microbes associated with plants in arsenic-contaminated soils from cattle dip sites, Ren Zhang, Somanath Bhat, Baldeo Chopra, Ying Yang, Hancai Chen, Xi Luo, Irina Mikheenko, Lukas van Zwieten, Zhi-Qiang Xu, and Ross M. Lilley

Papers from 2006

PDF

Asymmetric synthesis of anti-1,2-amino alcohols via the Borono-Mannich reaction: a formal synthesis of (-)-swainsonine, Christopher W. G. Au and Stephen G. Pyne

PDF

Synthesis of some cyclic indolic peptoids as potential antibacterials, Vicki S. Au, John B. Bremner, Jonathan Coates, Paul A. Keller, and Stephen G. Pyne

An estrogen-platinum terpyridine conjugate: DNA and protein binding and cellular delivery, Jennifer L. Beck, Stephen F. Ralph, Robert Price, Stephen James Watt, Julie Davis, Richard Pither, Michael J. Hannon, Philip S. Green, Dianne M. Fisher, Karen J. Sanders, Nathaniel W. Alcock, Peter J. Derrick, Philip R. Barker, Alison Rodger, and Margaret Sheil

A mass spectrometric investigation of the binding of gold antiarthritic agents and the metabolite [Au(CN)2]- to human serum albumin, Jennifer L. Beck, Stephen F. Ralph, and Jihan H. Talib

DNA - ligand complexes, Jennifer L. Beck and Margaret Sheil

PDF

Proteomic dissection of DNA polymerization, Jennifer L. Beck, Thitima Urathamakul, Stephen James Watt, Margaret Sheil, Patrick M. Schaeffer, and Nicholas E. Dixon

PDF

Tandem mass spectrometry reveals the quaternary organization of macromolecular assemblies, J L Benesch, Andrew Aquilina, Brandon T. Ruotolo, Frank Sobott, and C V Robinson

Multiple chromatin modifications important for gene expression changes in cardiac hypertrophy, Andrew J. Bingham, Lezanne Ooi, and Ian Wood

Ozonolysis of phospholipid double bonds during electrospray ionization: a new tool for structure determination, Stephen J. Blanksby, Michael Thomas, and Todd W. Mitchell

Isolation and NMR spectroscopic clarification of the alkaloid 1,3,7-trimethylguanine from the ascidian Eudistoma maculosum, John B. Bremner, Yoke J. Berry, Andrew R. Davis, and Siritron Samosorn

Constituents of medicinal plants of Lombok: a new antibacterial alkaloid from Voacanga foetida (B1.) Rolfe, John B. Bremner and Surya Hadi

PDF

Novel polycyclic Diels-Alder adducts from ring distorted 3-aza[5] and 3-aza[6] (1,7) napthalenophanes, John B. Bremner and Wasna Jaturonusmee

Constituents of the essential oil from aerial parts of Chromolaena odorata from Thailand, John B. Bremner, Jurgen Korth, Apiwat Baramee, Boonsom Liawruangrath, Saisunee Liawruangrath, N Pisutthanan, and a apisariyakul

A new flavonoid from Chromolaena odorata, John B. Bremner, Boonsom Liawruangrath, Saisunee Liawruangrath, and N Pisutthanan

Conjugating berberine to a multidrug resistance pump inhibitor creates an effective antimicrobial, John B. Bremner, Siritron Samosorn, Anthony Ball, Gabriele Casadei, Terence I. Moy, Frederik M. Ausubel, and Kim Lewis

Synthesis of functionalised 2-aryl-5-nitro-1H-indoles and their activity as bacterial NorA efflux pump inhibitors, John B. Bremner, Siritron Samosorn, Anthony Ball, and Kim Lewis

The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype, Alexander W. Bruce, Alena Krejci, Lezanne Ooi, James Deuchars, Ian C. Wood, Vladimir Dolezal, and Noel J. Buckley

PDF

Evidence from mitochondrial genomics on interordinal relationships in insects, Stephen L. Cameron, Andrew T. Beckenbach, Mark P. Dowton, and Michael F. Whiting

PDF

Trigger for Group A Streptococcal M1T1 Invasive Disease, J. N. Cole, Jason D. McArthur, F. C. McKay, Martina L. Sanderson-Smith, Amanda J. Cork, Marie Ranson, M. Rohde, A. Itzek, H. Sun, D. Ginsburg, M. Kotb, V. Nizet, G. S. Chhatwal, and Mark J. Walker

Genotoxicity and transmission electron microscopy studies of molybdocene dichloride, Carolyn T. Dillon, Margaret M. Harding, Kate S. Campbell, and Amalanie J. Foster

The endothelium-derived hyperpolarizing factor, H2O2, promotes metal-ion efflux in aortic endothelial cells: elemental mapping by a hard x-ray microprobe, Carolyn T. Dillon, Roland Stocker, H.H. Harris, B. Lai, Z. Cai, Peter A. Lay, Jade B. Aitken, Paul K. Witting, and Benjamin S. Rayner

Cell-free protein synthesis, Nicholas E. Dixon

Molecular analyses of the Apocrita (Insecta: Hymenoptera) suggest that the Chalcidoidea are sister to the diaprioid complex, Mark P. Dowton and Lyda Castro

Mitochondrial genomes of Vanhornia eucnemidarum (Apocrita: Vanhorniidae) and Primeuchroeus spp. (Aculeata: Chrysididae): evidence of rearranged mitochondrial genomes within the Apocrita (Hymenoptera), Mark P. Dowton, Kalani R. Ruberu, and Lyda Castro

PDF

An epididymal form of cauxin, a carboxylesterase-like enzyme, is present and active in mammalian male reproductive fluids, Heath W. Ecroyd, Maya Belghazi, JL Dacheux, M Miyazaki, T Yamashita, and JL Gatti

Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: Insights into substrate recognition and the mechanism of catalysis, Stephen C. Graham, Penelope E. Lilley, Mihwa Lee, Patrick M. Schaeffer, Andrew V. Kralicek, Nicholas E. Dixon, and J Mitchell Guss

PDF

Synthesis and In Vitro Binding of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides for the Peripheral Benzodiazepine Binding Sites, T. P. Homes, F. Mattner, Paul A. Keller, and A. Katsifis

PDF

Helicase-binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis, Charikleia Ioannou, Patrick M. Schaeffer, Nicholas E. Dixon, and Panos Soultanas

PDF

Polyamide platinum anti-cancer complexes designed to target specific DNA sequences, David Jaramillo, Nial J. Wheate, Stephen F. Ralph, Warren A. Howard, Yitzhak Tor, and Janice Aldrich-Wright

Structure determination of protein-ligand complexes by transferred paramagnetic shifts, Michael John, Guido Pintacuda, Ah-Young Park, Nicholas E. Dixon, and Gottfried Otting

PDF

Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication, Rory Johnson, Richard J. Gamblin, Lezanne Ooi, Alexander W. Bruce, Ian J. Donaldson, David R. Westhead, Ian Wood, Richard M. Jackson, and Noel J. Buckley

Simultaneous determination of isoflavones and lignans at trace levels in natural waters and wastewater samples using liquid chromatography/electrospray ionization ion trap mass spectrometry, Jinguo Kang, William E. Price, and Larry A. Hick

Product class 4: carboxylic acid anhydrides and their sulfur, selenium, and tellurium derivatives, Paul A. Keller

PDF

The Role of the HPA Axis in Psychiatric Disorders and CRF Antagonists as Potential Treatments, Paul A. Keller, A. McCluskey, J. Morgan, and S. M. O'Connor

Alk-1-ene-1,1-diamines with retention of functional group, Paul A. Keller and Jody Morgan

PDF

Reactions of Iminoglycines with C60 Fullerene and their Unambiguous Characterisation using NMR Spectroscopy, Paul A. Keller, Stephen G. Pyne, and Bill C. Hawkins

PDF

Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit, Max A Keniry, Ah-Young Park, Elisabeth A. Owen, Samir M. Hamdan, Guido Pintacuda, Gottfried Otting, and Nicholas E. Dixon

Protective effects of cardiotrophin-1 on injured neurons, Hongyun Li

PDF

Domains of group A streptococcal M protein that confer resistance to phagocytosis, opsonization and protection: implications for vaccine development., Jason D. McArthur and Mark J. Walker

A molecular mousetrap determines polarity of termination of DNA replication in E. coli, Mark D. Mulcair, Patrick M. Schaeffer, Aaron J. Oakley, Hannah F. Cross, Cameron Neylon, Thomas M. Hill, and Nicholas E. Dixon

Mechanism and Putative Structure of B0-like Neutral Amino Acid Transporters., Megan O'Mara, Aaron Oakley, and Stefan Broer

BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression, Lezanne Ooi, Nikolai D. Belyaev, Katsuhide Miyake, Ian C. Wood, and N. Buckley

15N-Labelled proteins by cell-free protein synthesis. Strategies for high-throughput NMR studies of proteins and protein-ligand complexes, Kiyoshi Ozawa, Peter S.C Wu, Nicholas E. Dixon, and Gottfried Otting

PDF

Microwave-assisted facile synthesis and crystal structure of cis-9,10,11,15-tetrahydro-9,10[3'4']-furanoanthracene-12,14-dione, Weerachai Phutdhawong, Duang Buddhasukh, Stephen G. Pyne, Apinpus Rujiwatra, and Chaveng Pakawatchai

Fast assignments of 15N-HSQC spectra of proteins by paramagnetic labeling, Guido Pintacuda, Thomas Huber, Max A Keniry, Ah-Young Park, Nicholas E. Dixon, and Gottfried Otting

Lanthanide labeling offers fast NMR approach to 3D structure determinations of protein-protein complexes, Guido Pintacuda, Ah-Young Park, Max A Keniry, Nicholas E. Dixon, and Gottfried Otting

Composition and antituberculosis activity of the volatile oil of Heliotropium indicum Linn. growing in Phitsanulok, Thailand, Stephen G. Pyne, Jurgen Korth, Boonsom Liawruangrath, Saisunee Liawruangrath, and Theeraphan Machan

Electroless recovery of silver by inherently conducting polymer powders, membranes and composite materials, Stephen F. Ralph, Roza Dimeska, Gordon G. Wallace, and Paul Murray

Electrosynthesis of novel photochemically active inherently conducting polymers using an ionic liquid electrolyte, Stephen F. Ralph, Chee O. Too, Gordon G. Wallace, and Paul Murray

The urokinase/PAI-2 complex: A new high affinity ligand for the endocytosis receptor low density lipoprotein receptor-related protein, Marie Ranson, David Croucher, and Darren Saunders

PDF

The Maintenance of High Affinity Plasminogen Binding by Group A Streptococcal Plasminogen-binding M-like Protein Is Mediated by Arginine and Histidine Residues within the a1 and a2 Repeat Domains., Martina L. Sanderson-Smith, Mark J. Walker, and Marie Ranson

Phytochemical studies on Stemona plants: isolation of new tuberostemonine and stemofoline alkaloids, Thanapat Sastraruji, Araya Jatisatienr, Kritchaya Issakul, Stephen G. Pyne, Alison T. Ung, Wilford Lie, and Morwenna C. Baird

Efficient χ-tensor determination and NH assignment of paramagnetic proteins, Christophe Schmitz, Michael John, Ah-Young Park, Nicholas E. Dixon, Gottfried Otting, Guido Pintacuda, and Thomas Huber

PDF

Application of surrogate methods for assessing the bioavailability of PAHs in sediments to a sediment ingesting bivalve, Stuart L. Simpson, Victoria L. Burston, Dianne F. Jolley, and Kim Chau