Molecular Horizons - formerly the Centre for Medical and Molecular Bioscience (CMMB) - brings together a multidisciplinary team of chemists and biologists with a common interest in the molecular basis of disease and disease prevention from the School of Chemistry and School of Biological Sciences at the University of Wollongong.

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Papers from 2004

Electrospray mass spectrometry of gas phase macromolecular complexes, Margaret M. Sheil, Jennifer L. Beck, Rajesh Gupta, Stephen Watt, Susan E. Brown, and Nicholas E. Dixon

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Metal equilibration and bioavailability in laboratory-contaminated (spiked) sediments used for the development of whole-sediment toxicity tests, Stuart L. Simpson, Brad M. Angel, and Dianne F. Jolley

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Processes controlling metal transport and retention as metal-contaminated groundwaters efflux through estuarine sediments, Stuart L. Simpson, Edward J. Maher, and Dianne F. Jolley

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Asymmetric Synthesis of (+)-1-Epiaustraline and Attempted Synthesis of Australine, Minyan Tang and Stephen G. Pyne

Gold recovery using inherently conducting polymer coated textiles, George Tsekouras, Stephen F. Ralph, William E. Price, and Gordon G. Wallace

"Pruning" of alloreactive CD4+ T cells using 5- (and 6-)carboxyfluorescein diacetate succinimidyl ester prolongs skin allograft survival, Debbie Watson, Geoff Yu Zhang, Mary Sartor, and Stephen I. Alexander

Inhibition of Protein Interactions with the β2 Sliding Clamp of Escherichia coli DNA Polymerase III by Peptides from β2-Binding Proteins, Gene Wijffels, Brian P. Dalrymple, Pavel Prosselkov, Kritaya Kongsuwan, Vidana Chandana Epa, Penelope E. Lilley, Slobodan Jergic, Jens Buchardt, Susan E. Brown, Paul F. Alewood, Philip A. Jennings, and Nicholas E. Dixon

Effect of methylation on the stability and solvation free energy of amylose and cellulose fragments: a molecular dynamics study, Haibo Yu, Manfred Amann, Tomas Hansson, Jutta Koehler, Guenter Wich, and Wilfred van Gunsteren

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Molecular dynamics simulations of peptides containing an unnatural amino acid: Dimerization, folding, and protein binding, Haibo Yu, Xavier Daura, and Wilfred van Gunsteren

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Charge-on-spring polarizable water models revisited: From water clusters to liquid water to ice, Haibo Yu and Wilfred van Gunsteren

Papers from 2003

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Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry, Jennifer L. Beck, Rajesh Gupta, Thitima Urathamakul, Nyree L. Williamson, Margaret Sheil, Janice Aldrich-Wright, and Stephen F. Ralph

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Cell surface antigens of Mycoplasma species bovine group 7 bind and activate plasminogen, Kylie Bower, Steven Djordjevic, Nicholas M Andronicos, and Marie Ranson

Gold recovery using fabrics coated with conducting polymers, Jie Ding, Violetta Misoska, William E. Price, Stephen F. Ralph, George Tsekouras, and Gordon G. Wallace

Recovery of gold cyanide using inherently conducting polymers, Jie Ding, William E. Price, Stephen F. Ralph, and Gordon G. Wallace

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Endogenous redox activity in mouse spermatozoa and its role in regulating the tyrosine phosphorylation events associated with sperm capacitation, Heath W. Ecroyd, Russell C. Jones, and Robert J. Aitken

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Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation, Heath W. Ecroyd, Russell C. Jones, and Robert J. Aitken

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Evolution of chemical contaminant and toxicology studies, part 1 - an overview, Dianne F. Jolley, Glennys A. O'Brien, and Robert John Morrison

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Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by ph-sensitive disruption of endosomal vesicles, Rachel A. Jones, C. Y. Cheung, F. E. Black, J. K. Zia, P. S. Stayton, A. S. Hoffman, and Mark R. Wilson

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Novel Pharmacophore Based Methods Reveal Gossypol as a Reverse Transcriptase Inhibitor, Paul A. Keller, C. Birch, S. P. Leach, D. Tyssen, and R. Griffith

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The prevention of preterm labour – Corticotropin Releasing Hormone type 1 receptors as a target for drug design and development, Paul A. Keller, K. Kirkwood, J. Morgan, S. Westcott, and A. McCluskey

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Chemo-enzymatic synthesis of (-)-epipentenomycin I, Tawesin Klomklao, Stephen G. Pyne, Apiwat Baramee, Brian W. Skelton, and Allan H. White

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Stemocurtisine, the first pyrido[1,2-a]azapine Stemona alkaloid, Pitchaya Mungkornasawakul, Stephen G. Pyne, Araya Jatisatienr, Damrat Supyen, Wilford Lie, Alison T. Ung, Brian W. Skelton, and Allan H. White

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Flexibility revealed by the 1.85 Å crystal structure of the β sliding-clamp subunit of Escherichia coli DNA polymerase III, Aaron J. Oakley, Pavel Prosselkov, Gene Wijffels, Jennifer L. Beck, Matthew CJ Wilce, and Nicholas E. Dixon

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Evolution of chemical contaminant and toxicology studies, part 2- case studies of Selenium and Arsenic, Glennys O'Brien, Dianne Jolley, and Robert John Morrison

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Distribution of intimin subtypes among Escherichia coli isolates from ruminant and human sources, Vidiya Ramachandran, Kim Brett, Michael A Hornitzky, Mark Dowton, Karl A Bettelheim, Mark J. Walker, and Steven P. Djordjevic

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Asymmetric synthesis of (-)-7-epiaustraline and (+)-1,7-diepiaustraline, Minyan Tang and Stephen G. Pyne

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Development of a simple, self-consistent polarizable model for liquid water, Haibo Yu, Tomas Hansson, and Wilfred van Gunsteren

Papers from 2002

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Streptococcus pyogenes prtFII, but not sfbI, sfbII or fbp54, is represented more frequently among invasive-disease isolates of tropical Australia, A. Delvecchio, B. J. Currie, Jason D. McArthur, Mark J. Walker, and K. S. Sriprakash

Electrochemical behaviour of polypyrrole/sulfated poly(B-hydroxyether) composites, Jie Ding, William E. Price, Stephen F. Ralph, and Gordon G. Wallace

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Synthesis of chiral allylic amines via palladium(0) catalysed allylations of allylic carbonates with chiral sulfinamide anions, Zemin Dong and Stephen G. Pyne

NMR analysis of in vitro-synthesized proteins without purification: a high-throughput approach, Laurent Guignard, Kiyoshi Ozawa, Sharon E. Pursglove, Gottfried Otting, and Nicholas E. Dixon

Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (E) subunit of Escherichia coli DNA polymerase III, Samir Hamdan, Esther M. Bulloch, Philip R. Thompson, Jennifer L. Beck, Ji Yeon Yang, Jeffrey A. Crowther, Penelope E. Lilley, Paul D. Carr, David L. Ollis, Susan E. Brown, and Nicholas E. Dixon

Detecting mitochondrial permeability transition by confocal imaging of intact cells pinocytically loaded with calcein, Rachel A. Jones, Alison Smail, and Mark R. Wilson

Use of electrospray ionization mass spectrometry to study binding interactions between a replication terminator protein and DNA, Amit Kapur, Jennifer L. Beck, Susan E. Brown, Nicholas E. Dixon, and Margaret Sheil

Evidence that clusterin has discrete chaperone and ligand binding sites, Johnathon N. Lakins, Stephen Poon, Simon B. Easterbrook-Smith, John A. Carver, Martin P. R. Tenniswood, and Mark R. Wilson

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Synthesis of (+/-)epipentenomycin I and III, Weerachai Phutdhawong, Stephen G. Pyne, Apiwat Baramee, Duang Buddhasukh, Brian W. Skelton, and Allan H. White

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Mildly acidic pH activates the extracellular molecular chaperone clusterin, Stephen Poon, M. S. Rybchyn, S. B. Easterbrook-Smith, J. A. Carver, G. J. Pankhurst, and Mark R. Wilson

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Clusterin is an extracellular chaperone that specifically interacts with slowly aggregating proteins on their off-folding pathway, Stephen Poon, T. M. Treweek, Mark R. Wilson, Simon B. Easterbrook-Smith, and John A. Carver

Electrohydrodynamic synthesis of polypyrrole coated polyurethane colloidal dispersions using the electrocatalyst Tiron, David Reece, Peter C. Innis, Stephen F. Ralph, and Gordon G. Wallace

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Considerations for capping metal-contaminated sediments in dynamic estuarine environments, Stuart L. Simpson, Ian D. Pryor, Ben R. Mewburn, Graeme E. Batley, and Dianne F. Jolley

Papers from 2001

Infiltration of canonical Vγ4/Vδ1 γδ T cells in an adriamycin-induced progressive renal failure model, Takashi Ando, Huiling Wu, Debbie Watson, Tadashi Hirano, Hideki Hirakata, Masatoshi Fujishima, and John F. Knight

The DnaB.DnaC complex: a structure based on asymmetric interactions among dimers assembled around an occluded channel, Monserrat Barcena, Teresa Ruiz, Luis Enrique Donate, Susan E. Brown, Nicholas E. Dixon, Michael Radermacher, and Jose Maria Carazo

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Indole derivatives from the egg masses of Muricid molluscs, Kirsten Benkendorff, John B. Bremner, and Andrew R. Davis

A universal protein-protein interaction motif in the eubacterial DNA replication and repair systems, Brain P. Dalrymple, Kritaya Kongsuwan, Gene Wijffels, Nicholas E. Dixon, and Philip A. Jennings

Electrochemically controlled transport of metal ions across polypyrrole membranes using a flow-through cell, Michael Davey, Stephen F. Ralph, Chee O. Too, Gordon G. Wallace, and Ashton Partridge

Metal separation using polypyrroles containing chelating agents, Jie Ding, Violetta Misoska, William E. Price, Stephen F. Ralph, and Gordon G. Wallace

Transport of gold across composite poly(bithiophene) membranes, Jie Ding, William E. Price, Stephen Ralph, and Gordon G. Wallace

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Initial studies on alkaloids from Lombok medicinal plants, Surya Hadi and John B. Bremner

Health benefits of dietary phytooestrogens, Theresa A. Larkin, Lee Astheimer, and William E. Price

Disproportionation of a model chromium(V) complex causes extensive chromium(III)-DNA binding in vitro, Aviva Levina, Peter A. Lay, and Nicholas E. Dixon

Electrochemical synthesis of pyrrole through a polystyrene opal matrix, Violetta Misoska, William E. Price, Stephen F. Ralph, and Gordon G. Wallace

Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: Relevance to chromium genotoxicity, David I. Pattison, Michael J. Davies, Aviva Levina, Nicholas E. Dixon, and Peter A. Lay

Separation and recovery of gold and other metals using conducting polymers, William E. Price, Stephen F. Ralph, and Gordon G. Wallace

The effect of processing conditions on the physico-chemical changes during dehydration of prunes, Henry T. Sabarez and William E. Price

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Detection of P2X purinergic receptors on human B lymphocytes, Ronald Sluyter, J A. Barden, and James Wiley

Infiltration by inflammatory cells required for solar-simulated ultraviolet radiation enhancement of skin tumor growth, Ronald Sluyter and Gary M. Halliday

Protective immunity to UV radiation-induced skin tumours induced by skin grafts and epidermal cells, Ronald Sluyter, Kylie S. Yuen, and Gary M. Halliday

Genetic polymorphisms of the human P2X7 receptor and relationship to function, James Wiley, Ben J. Gu, Weiyi Zhang, Rebecca A. Worthington, L Phuong Dao-Ung, Anne Shemon, Ronald Sluyter, Stephen Liang, and J A. Barden

Design of new selective inhibitors of cyclooxygenase-2 by dynamic assembly of molecular building blocks, Jiang Zhu, Haibo Yu, Hao Fan, Haiyan Liu, and Yunyu Shi

Papers from 2000

Conducting Polyaniline/Calixarene salts: synthesis and properties, Jelders M Davey, Chee O. Too, Stephen F. Ralph, Leon A. Kane-Maguire, Ashton Partridge, and Gordon G. Wallace

Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state, Stephen Poon, Simon B. Easterbrook-Smith, Mark S. Rybchyn, John A. Carver, and Mark R. Wilson

The role of the waxy skin layer on moisture loss during dehydration of prunes, William E. Price, Henry T. Sabarez, Richard Storey, and Philip J. Black

Volatile changes during dehydration of d'Agen prunes, Henry T. Sabarez, William E. Price, and Jurgen Korth

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Enhanced tumor growth in UV-irradiated skin is associated with an influx of inflammatory cells into the epidermis, Ronald Sluyter and Gary M. Halliday

Sequence and diversity of the rat delta T-cell receptor, Debbie Watson, Takashi Ando, and John F. Knight

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Single Nucleotide Primer Extension (SNuPE) analysis of the G6PD gene in somatic cells and oocytes of a kangaroo (Macropus robustus), Debbie Watson, Anita S. Jacombs, David A. Loebel, Edward S. Robinson, and Peter G. Johnston

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Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence, Nicholas P. West, Heidrun Jungnitz, John Fitter, Jason D. McArthur, Carlos Guzman, and Mark J. Walker

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Clusterin protein diversity in the primate eye, Paul Wong, Bruce A. Pfeffer, Steven L. Bernstein, Michelle L. Chambers, Gerald J. Chader, Zahra F. Zakeri, Yan-Q Wu, Mark Wilson, and S Patricia Becerra

Papers from 1999

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Electrospray ionisation mass spectrometry of ruthenium and palladium complexes with oligonucleotides, Jennifer L. Beck, Amy Humphries, Margaret Sheil, and Stephen F. Ralph

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[60]Fullerene Amino Acids and Related Derivatives, Glenn A. Burley, Paul A. Keller, and Stephen G. Pyne

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Synthesis of thiazole analogues of the immunosuppressive agent (1R,2S,3R)-2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole, George R. Jeoffreys, Alison T. Ung, Stephen G. Pyne, Brian W. Skelton, and Allan H. White

Microstructure of the skin of d'Agen plums, R Storey and William E. Price

Papers from 1998

p, T dependence of self-diffusion in 2-fluoroethanol, 2,2 difluoroethanol and 2,2,2-trifluoroethanol, Thomas Gross, N Karge, and William E. Price

Limited genetic control of specific IgE responses to rye grass pollen allergens in Australian twins, Ronald Sluyter, Euan R. Tovey, David L. Duffy, and Warwick J. Britton

Immunoblotting analysis of twin sera provides evidence for limited genetic control of specific IgE responses to house dust mite allergens, Euan R. Tovey, Ronald Sluyter, David L. Duffy, and Warwick J. Britton

Synthesis, characterisation and transport properties of layered conducting electroactive polypyrrole membranes, Huijun Zhao, William E. Price, and Gordon G. Wallace

Papers from 1997

The p,T-dependence of self-diffusion in fluid ammonia, Thomas Gross, J Buchhauser, William E. Price, Igor N. Tarassov, and Hans D. Ludemann

The effect of different electrical stimuli on the oxidation/reduction behaviour of polypyrrole-pTS: A study using the electrochemical quartz crystal microbalance, Abdolreza Mirmohseni-Namin, William E. Price, and Gordon G. Wallace

Dehydration of prunes: Kinetic aspects, William E. Price, Henry Sabarez, Leanne G. Laajoki, and Lawrence A. Woolf

Modelling the kinetics of drying of d'Agen plums (Prunus domestica), Henry Sabarez, William E. Price, Phillip J. Back, and Lawrence A. Woolf

Kinetics of carbohydrate change during dehydration of d'Agen prunes, Leanne G. Wilford, Henry Sabarez, and William E. Price

Papers from 1996

Effect of thermal treatment on the electroactivity of polyaniline, Reza Ansari, William E. Price, and Gordon G. Wallace

Epidermal Langerhans' cell induction of immunity against an ultraviolet-induced skin tumour, Lois L. Cavanagh, Ronald Sluyter, Kirsten G. Henderson, Ross StC Barnetson, and Gary M. Halliday

Aqueous extraction of solubles from oranges: A kinetic study, Clark Chambers, Kim Exaudi-Larsen, and William E. Price

Factors influencing the drying of prunes. 1. Effects of temperature upon the kinetics of moisture loss during drying, Gail M. Newman, William E. Price, and Lawrence A. Woolf

Modulation of Ia+ Langerhans cell numbers in vivo by cultured epidermis derived supernatants and by GM-CSF, Gabrielle M. O'Sullivan, Ronald Sluyter, Christopher M. Boswell, Ross StC Barnetson, and Gary M. Halliday

Erratum: Use of experimental diffusion coefficients to probe solute-solute and solute-solvent interactions in electrolyte solutions (Journal of Physical Chemistry (1996) 100 (1406)), William E. Price, Reginald S. Mills, and Lawrence A. Woolf

Use of experimental diffusion coefficients to probe solute-solute and solute-solvent interactions in electrolyte solutions, William E. Price, Reginald S. Mills, and Lawrence A. Woolf

Parameters influencing transport across conducting electroactive polymer-membranes, Huijun Zhao, William E. Price, Chee O. Too, Gordon G. Wallace, and Dezhi Zhou

Papers from 1995

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Effect of organic solvents on the separation of benzoic acids by capillary electrophoresis, Young J. Lee, William E. Price, and Margaret Sheil

Intradiffusion coefficients for perchlorate ions in zinc perchlorate and zinc chloride solutions at 25 degrees C: Comparing transport properties of zinc chloride and zinc perchlorate systems, William E. Price and Lawrence A. Woolf

Papers from 1994

Scratching the surface of intelligent materials: characterisation methods for conducting polymer films, Zhao Huijun, Abdolreza Mirmohseni-Namin, William E. Price, Afshad Talaie, and Gordon G. Wallace

Effect of the counterion employed during synthesis on the properties of polypyrrole membranes, Huijun Zhao, William E. Price, and Gordon G. Wallace

Papers from 1992

Intradiffusion coefficients for iron and water and shear viscosities in aqueous iron(II) perchlorate solutions at 25C, William E. Price and Lawrence A. Woolf

Electrochemically controlled transport of potassium chloride across a conducting electro-active polymer membrane, Huijun Zhao, William E. Price, and Gordon G. Wallace

Papers from 1991

Intradiffusion and viscosity measurements in acidified iron(III) chloride solutions at 25°C, Allan J Easteal, Rakesh K. Malhotra, William E. Price, and Lawrence A. Woolf

Ion pairing and redissociation in concentrated aqueous solutions of 2:2 electrolytes. A transport coefficient study of aqueous ZnSO4, William E. Price and Hermann Weingartner

Inferences on dynamic water structure in aqueous solutions from diffusion measurements, William E. Price and Lawrence A. Woolf

Papers from 1990

Thermodynamic and transport properties of 1, 2-dichloroethane, Rakesh K. Malhotra, William E. Price, Lawrence A. Woolf, and Allan J Easteal

Intradiffusion coefficients for zinc and water and shear viscosities in aqueous zinc(II) perchlorate solutions at 25°C, William E. Price, Lawrence A. Woolf, and Kenneth R Harris