RIS ID
21133
Abstract
The novel laudanosine dimers in which two laudanosine units are linked via a C-2′ biaryl bond have been prepared by a sequence that involves formation of the biaryl bond first and then formation of the isoquinoline rings. Two of these compounds showed higher cytostatic activity on three cancer cell lines than thalicarpine.
Included in
Life Sciences Commons, Physical Sciences and Mathematics Commons, Social and Behavioral Sciences Commons
Publication Details
Taylor, S. R., Ung, A. T. & Pyne, S. G. (2007). The synthesis of 2'',2''-bis-benzylisoquinolines and their cytostatic activities. Tetrahedron, (63), 10896-10901.