Short acquisition time PET quantification using MRI-based pharmacokinetic parameter synthesis

Authors

Catherine J. Scott, University College London
Jieqing Jiao, University College London
Manuel J. Cardoso, University College London
Andrew Melbourne, University College London
Enrico De vita, University College London
David L. Thomas, University College London
Ninon Burgos, University College London
Pawel Markiewicz, University College London
Jonathan M. Schott, University College London
Brian F. Hutton, University of WollongongFollow
Sebastien Ourselin, University College London

RIS ID

116627

Publication Details

Scott, C. J., Jiao, J., Cardoso, M. J., Melbourne, A., De Vita, E., Thomas, D. L., Burgos, N., Markiewicz, P., Schott, J. M., Hutton, B. F. & Ourselin, S. (2017). Short acquisition time PET quantification using MRI-based pharmacokinetic parameter synthesis. Lecture Notes in Computer Science, 10434 737-744.

Abstract

Positron Emission Tomography (PET) with pharmacokinetic (PK) modelling is a quantitative molecular imaging technique, however the long data acquisition time is prohibitive in clinical practice. An approach has been proposed to incorporate blood flow information from Arterial Spin Labelling (ASL) Magnetic Resonance Imaging (MRI) into PET PK modelling to reduce the acquisition time.