The Illawarra Health and Medical Research Institute is a partnership between the University of Wollongong and the South Eastern Sydney Illawarra Area Health Service. IHMRI's research focuses on health and medical issues that are common in the Illawarra region and is aimed at improving the health and well being of the local community. IHMRI's goal is to foster research collaboration through the IHMRI Research Network, creating a centre of excellence and innovation that represents the focal point of health and medical research in this region.
Papers from 2009
A metabolite profiling approach to identify biomarkers of flavonoid intake in humans, Wai Mun Loke, Andrew M. Jenner, Julie M. Proudfoot, Allen J. McKinley, Jonathan M. Hodgson, Barry Halliwell, and Kevin D. Croft
Elevated oxidative stress, iron accumulation around microvessels and increased 4-hyroxynonenal immunostaining in zone 1 of the liver acinus in hypercholesterolemic rabbits, Wei-Yi Ong, Andrew M. Jenner, Ning Pan, Choon-Nam Ong, and Barry Halliwell
Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons, Kim W Scott, S L Chan, A F Hill, G J Guillemin, and B Garner
Imaging of single cells and tissue using MeV ions, F Watt, A A. Bettiol, J. A van Kan, M D. Ynsa, Ren Minqin, R Rajendran, Cui Huifang, Shen Fwu-Shen, and A M. Jenner
Changes in alternative brain-derived neurotrophic factor transcript expression in the developing human prefrontal cortex, Jenny Wong, Maree J. Webster, Hope Cassano, and Cynthia S. Weickert
Transcriptional interaction of an estrogen receptor splice variant and ErbB4 suggests convergence in gene susceptibility pathways in schizophrenia, Jenny Wong and Cynthia Shannon Weickert
Elevation of oxidative-damage biomarkers during aging in F2 hybrid mice: Protection by chronic oral intake of resveratrol, Yee Ting Wong, Jan Gruber, Andrew M. Jenner, Mary Pei-Ern Ng, Runsheng Ruan, and Francis Eng Hock Tay
Papers from 2008
Strategic male calling behavior in an Australian Terrestrial Toadlet (Pseudophryne bibronii), Phillip Byrne
Effect of a refuge from persistent male courtship in the Drosophila laboratory environment, Phillip G. Byrne, W R Rice, and G R Rice
Simultaneous polyandry increases fertilisation success in an African foam-nesting tree frog, Phillip G. Byrne and M J Whiting
ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro, S L Chan, Woojin Scott Kim, J B Kwok, A F Hill, R Cappai, Kerry-Anne Rye, and Brett Garner
Regulation of alpha-synuclein expression by liver X receptor ligands in vitro, Danni Cheng, Woojin Scott Kim, and Brett Garner
Changes in cytochrome P450 side chain cleavage expression in the rat hippocampus after kainate injury, W-J Chia, Andrew M. Jenner, A A Farooqui, and W-Y Ong
The comparative biology of neuromelanin and lipofuscin in the human brain, K L Double, V N Dedov, H Fedorow, E Kettle, G Halliday, Brett Garner, and U T Brunk
Macrophage apolipoprotein-E knockdown modulates caspase-3 activation without altering sensitivity to apoptosis, D A Elliott, Woojin Scott Kim, D A Jans, and Brett Garner
Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats, Y. Fan, L.L-Y Wu, Hongyun Li, Y. Wang, and Xin-Fu Zhou
Myriocin as an atherosclerosis inhibitor, Brett Garner
Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice, Elias N. Glaros, Woojin Scott Kim, C M Quinn, W Jessup, Kerry-Anne Rye, and Brett Garner
Reduction of plasma glycosphingolipid levels has no impact on atherosclerosis in apolipoprotein E-null mice, Elias N. Glaros, Woojin Scott Kim, Kerry-Anne Rye, J A Shayman, and Brett Garner
Analysis of apolipoprotein E nuclear localization using green fluorescent protein and biotinylation approaches, Woojin Scott Kim, D A Elliott, M Kockx, L Kritharides, Kerry-Anne Rye, D A Jans, and Brett Garner
Role of ATP-binding cassette transporters in brain lipid transport and neurological disease, Woojin Scott Kim, Cynthia Shannon Weickert, and Brett Garner
Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample, C-Y J Lee, Shizhen Huang, Andrew M. Jenner, and Barry Halliwell
Potential conversion of adult clavicle-derived chondrocytes into neural lineage cells in vitro, Hongyun Li and Xin-Fu Zhou
Microsatellite markers in the endangered Australian northern corroboree frog, Pseudophryne pengilleyi (Anura: Myobatrachidae) and amplification in other Pseudophryne species, M J Morgan, Phillip G. Byrne, C M Hayes, and J S Keogh
Modulation of brain metabolism by very low concentrations of the commonly used drug delivery vehicle dimethyl sulfoxide (DMSO), F A Nasrallah, Brett Garner, Graham E Ball, and C Rae
Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia, Cynthia Shannon Weickert, A L Miranda-Angulo, Jenny Wong, W R Perlman, S E Ward, V Radhakrishna, R E Straub, D R Weinberger, and J E Kleinman
Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis, Jenny Wong, C M Quinn, I C Gelissen, and A Brown
The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation, Jenny Wong, C M Quinn, I C Gelissen, W Jessup, and A Brown
OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages, D Yan, M I Mayranpaa, Jenny Wong, J Perttila, M Lehto, M Jauhiainen, P T Kovanen, C Enholm, A Brown, and V M Olkkonen
Papers from 2007
Terrestrial toadlets use chemosignals to recognise conspecifics, locate mates and strategically adjust calling behaviour, Phillip G. Byrne and J Scott Keogh
Apoptosis induces neuronal apolipoprotein-E synthesis and localization in apoptotic bodies, David A. Elliott, Woojin S. Kim, David A. Jans, and Brett Garner
Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration, Elias N. Glaros, Woojin S. Kim, Benjamin J. Wu, Cacang Suarna, Carmel M. Quinn, Kerry-Anne Rye, Roland Stocker, Wendy Jessup, and Brett Garner
Zinc supplementation inhibits lipid peroxidation and the development of atherosclerosis in rabbits fed a high cholesterol diet, Andrew M. Jenner, M Ren, Reshmi Rajendran, Pan Ning, B Huat, Frank Watt, and Barry Halliwell
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-β peptide generation, Woojin Kim, Aldwin Rahmanto, Alvin Kamili, Kerry-Anne Rye, Gilles J. Guillemin, Ingrid C. Gelissen, Wendy Jessup, Andrew F. Hill, and Brett Garner
Primary sensory neuron addition in the adult rat trigeminal ganglion: evidence for neural crest glio-neuronal precursor maturation, Alfonso Lagares, Hong-Yun Li, Xin-Fu Zhou, and Carlos Avendano
Isolation and characterization of neural crest progenitors from adult dorsal root ganglia, Hong-yun Li, Evonne Hwee Min Say, and Xin-Fu Zhou
The identification of antioxidants in dark soy sauce, Huansong Wang, Andrew M. Jenner, Chung-Yung J. Lee, Guanghou Shui, Soon Yew Tang, Matthew Whiteman, Markus R. Wenk, and Barry Halliwell
Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol, Jenny Wong, Carmel M. Quinn, and Andrew J. Brown
Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis, Jenny Wong, Carmel M. Quinn, Gilles Guillemin, and Andrew J. Brown
Roles of glial p75NTR in axonal regeneration, Xin-Fu Zhou and Hong-Yun Li
Papers from 2006
The legitimacy of my ethnographic gaze: context, methodology and insights from in the field, Lao PDR, K Alexander and D H R Spennemann
Evidence for adaptive male-mate choice in the fruit fly Drosophila melanogaster, Phillip G. Byrne and William R. Rice
Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: A link between a key cell proliferative pathway and membrane synthesis, X Du, Ika Kristiana, Jenny Wong, and A Brown
Investigation of the lipid component of neuromelanin, H Fedorow, R Pickford, E Kettle, M Cartwright, G Halliday, M Gerlach, P Riederer, and Brett Garner
Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury, Xin He, Andrew Jenner, Wei-Yi Ong, Akhlaq A. Farooqui, and Shutish C. Patel
HPLC analysis of discrete haptoglobin isoform N-linked oligosaccharides following 2D-PAGE isolation, Zhija He, L P. Aristoteli, L Kritharides, and Brett Garner
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells, Woojin Scott Kim, Gilles Guillemin, Elias N. Glaros, C K. Lim, and Brett Garner
Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons, Chor Koh, Matthew Whiteman, Qiao-Xin Li, Barry Halliwell, Andrew Jenner, Boon Wong, Katrina Laughton, Markus Wenk, Colin Masters, Philip Beart, Ora Bernard, and Nam Cheung
Cautions in the use of biomarkers of oxidative damage; the vascular and antioxidant effects of dark soy sauce in humans, Chung-Yung Lee, Helen Isaac, Huansong Wang, Shan Huang, Lee-Hua Long, Andrew Jenner, Ronan Kelly, and Barry Halliwell
Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota, Hui Lee, Andrew Jenner, Chin S. Low, and Yuan K. Lee
Potential artifacts in the measurement of DNA deamination, Kok Lim, Shan Huang, Andrew Jenner, Huansong Wang, Soon Y. Tang, and Barry Halliwell
Quantitative gas chromatography mass spectrometric analysis of 2'-deoxyinosine in tissue DNA, Kok Lim, Andrew Jenner, and Barry Halliwell
Overcoming original antigenic sin to generate new CD8 T cell IFN-y responses in an antigen-experienced host, Xiaosong Liu, Graham R. Leggatt, Ian H. Frazer, Ranjeny Thomas, Joanne Dyer, Germain J P Fernando, and Jie Zhong
Zinc supplementation decreases the development of atherosclerosis in rabbits, Minqin Ren, Reshmi Rajendran, Pan Ning, Benny Kwong Huat, Ong Nam, Frank Watt, Andrew Jenner, and Barry Halliwell
Assessing sexual conflict in the Drosophila melanogaster laboratory model system, William R. Rice, Andrew D. Stewart, Edward H. Morrow, Jodell E. Linder, Nicole Orteiza, and Phillip G. Byrne
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR, Jenny Wong, C M Quinn, and A Brown
Papers from 2005
Remating in Drosophila melanogaster: an examination of the trading-up and intrinsic male-quality hypotheses, Phillip G. Byrne and W R. Rice
Dolichol is the major lipid component of human substantia nigra neuromelanin, Heidi Fedorow, Russell Pickford, James M. Hook, Kay L. Double, Glenda M. Halliday, Manfred Gerlach, Peter Riederer, and Brett Garner
Assessing the potential for an ongoing arms race within and between the sexes: selection and heritable variation, Urban Friberg, Timothy A. Lew, Phillip G. Byrne, and William R. Rice
Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-Phenyl-2-decanoylamino-3-morpholino-1- propanol is a novel cholesterol efflux accelerator, Elias N. Glaros, W B. Kim, C M Quinn, Jenny Wong, I C Gelissen, W Jessup, and Brett Garner
Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?, Barry Halliwell, J J Rafter, and Andrew M. Jenner
Human fecal water content of phenolics: The extent of colonic exposure to aromatic compounds, Andrew M. Jenner, J J Rafter, and Barry Halliwell
Human fecal water inhibits COX-2 in colonic HT-29 cells: Role of phenolic compounds, P C Karlsson, U Huss, Andrew M. Jenner, Barry Halliwell, L Bohlin, and J J Rafter
Oxidative damage in mitochondrial DNA is not extensive, Kok Seong Lim, Kandiah Jeyaseelan, Matthew Whiteman, Andrew M. Jenner, and Barry Halliwell
Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARγ ligands, C M Quinn, W Jessup, Jenny Wong, L Kritharides, and A Brown
Phosphorylation of apolipoprotein-E at an atypical protein kinase CK2 PSD/E site in vitro, M. Raftery, R. Campbell, Elias Glaros, Kerry-Anne Rye, G. Halliday, W. Jessup, and Brett Garner
Papers from 2004
Two cases of thyroid carcinoma that were not stimulated by recombinant human thyotropin, Barbara Depczynski and Stephen Lillioja
Papers from 1988
Short-term energy balance: relationship with protein, William G. H Abbott, Barbara V. Howard, Laurent Christin, Daniel Freymond, Stephen Lillioja, Vicky L. Boyce, Thomas E. Anderson, Clifton Bogardus, and Eric Ravussin
Glucose-6-phosphate stimulatioin of human muscle glycogen synthase phosphate, Masamichi Okubo, Clifton Bogardus, S Lillioja, and David M. Mott
Increased rate of Cori cycle in obese subjects with NIDDM and effect of weight reduction, J K. Zawadzki, R Wolfe, D Mott, Stephen Lillioja, B Howard, and C Bogardus
Papers from 1987
Relationships between plasma lipoprotein concentrations and insulin action in an obese hyperinsulinemic population, W Abbott, Stephen Lillioja, A Young, J K. Zawadzki, H Yki-Jarvinen, L Christin, and B Howard
Recent epidemiological contributions to the pathogenesis and etiology of non-insulin dependent diabetes, P Bennett, C Bogardus, W C. Knowler, and Stephen Lillioja
Papers from 1986
Familial dependence of the resting metabolic rate, C Bogardus, S Lillioja, E Ravussin, W Abbott, J K. Zawadzki, A Young, W C. Knowler, R Jacobowitz, and P Moll
Increased resting metabolic rates in obese subjects with non-insulin-dependent diabetes mellitus and the effect of sulfonylurea therapy, C Bogardus, M Taskinen, J K. Zawadzki, Stephen Lillioja, D Mott, and B Howard
Comparison of glucose metabolism in adipocytes from Pima Indians and Caucasians, J E. Foley, Stephen Lillioja, J K. Zawadzki, and G R. Reaven
Insulin sensitivity in adipocytes from subjects with varying degrees of glucose tolerance, J E. Foley, P Thuillez, Stephen Lillioja, J K. Zawadzki, and C Bogardus
Free fatty acid metabolism and obesity in man: in vivo in vitro comparisons, Stephen Lillioja, J E. Foley, C Bogardus, D Mott, and B Howard
Glucose storage is a major determinant of in vivo "insulin resistance" in subjects with normal glucose tolerance, Stephen Lillioja, D Mott, J K. Zawadzki, A Young, W Abbott, and C Bogardus
Overnutrition induced decrease in insulin action for glucose storage: in vivo and in vitro in man, D Mott, Stephen Lillioja, and C Bogardus
Determinants of 24-hour energy expenditure in man: methods and results using a respiratory chamber, E Ravussin, Stephen Lillioja, T Anderson, L Christin, and C Bogardus
Papers from 1985
Relationship between degree of obesity and invivo insulin action in man, C Bogardus, Stephen Lillioja, D Mott, C Hollenbeck, and G R. Reaven
Relationship between obesity and maximal insulin-stimulated glucose uptake in vivo and in vitro in man, C Bogardus, Stephen Lillioja, D Mott, G R. Reaven, A Kashiwagi, and J E. Foley
Evidence for reduced thermic effect of insulin and glucose infusions in Pima Indians, C Bogardus, Stephen Lillioja, D Mott, J K. Zawadzki, A Young, and W Abbott
The effects of short-term overfeeding on adipocyte metabolism in Pima Indians, A Kashiwagi, D Mott, C Bogardus, Stephen Lillioja, G R. Reaven, and J E. Foley
Relationship between insulin-mediated glucose disposal and lipid metabolism in man, Stephen Lillioja, C Bogardus, D Mott, A Kennedy, W C. Knowler, and B Howard
Papers from 1984
Relationship between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects, C Bogardus, Stephen Lillioja, B Howard, G R. Reaven, and D Mott
Correlation between muscle glycogen synthase activity and in vivo insulin action in man, C Bogardus, Stephen Lillioja, K Stone, and D Mott
Sex difference in insulin-stimulated glucose transport in rat and human adipocytes, J E. Foley, A Kashiwagi, H H Chang, T Huecksteadt, Stephen Lillioja, M Verso, and G R. Reaven
In vitro insensitivity of glucose transport and antilipolysis to insulin due to receptor and postreceptor abnormalities in obese Pima Indians with normal glucose tolerance, A Kashiwagi, C Bogardus, Stephen Lillioja, T Huecksteadt, D Brady, M Verso, and J E. Foley