Year

2020

Degree Name

Doctor of Philosophy (Integrated)

Department

School of Chemistry and Molecular Bioscience

Abstract

Recent scientific advances in imaging technology mean the development of fluorescent and radiopharmaceutical probes have great potential for the measurement of pathological processes involved in various diseases, including neurodegenerative diseases and cancers. This thesis describes the design, synthesis, and biological studies of fluorescent and radiopharmaceutical (tau ligands) probes for imaging neurodegenerative diseases.

FoR codes (2008)

0304 MEDICINAL AND BIOMOLECULAR CHEMISTRY, 0305 ORGANIC CHEMISTRY, 1109 NEUROSCIENCES, 110313 Nuclear Medicine

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Unless otherwise indicated, the views expressed in this thesis are those of the author and do not necessarily represent the views of the University of Wollongong.