Year

2024

Degree Name

Doctor of Philosophy

Department

School of Chemistry and Molecular Bioscience

Abstract

The human gut microbiome confers many benefits to its host, therefore dysbiosis; an imbalance in microbial community composition, may have a negative impact on health. It is unclear however if dysbiosis is a consequence of a particular disease process, or a cause. This thesis explores the influence of gut microbiome on health outcomes and disease progression in the context of dietary fibre consumption and obesity, and peritoneal dialysis in patients with chronic kidney disease. This thesis also investigates the correlation between Crohn’s disease (CD) and genes expressed exclusively by blood monocytes in reponse to bacteria. Finally, this thesis explores antimicrobial resistance in bacteria isolated from retail chicken and pork meat sold in the Australian Capital Territory (ACT) and New South Wales (NSW).

FoR codes (2008)

0604 GENETICS, 0605 MICROBIOLOGY

Share

COinS
 

Unless otherwise indicated, the views expressed in this thesis are those of the author and do not necessarily represent the views of the University of Wollongong.