Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection

Publication Name

Medicina (Lithuania)

Abstract

Measles is an RNA virus infectious disease mainly seen in children. Despite the avail-ability of an effective vaccine against measles, it remains a health issue in children. Although it is a self-limiting disease, it becomes severe in undernourished and immune-compromised individuals. Measles infection is associated with secondary infections by opportunistic bacteria due to the immunosuppressive effects of the measles virus. Recent reports highlight that measles infection erases the already existing immune memory of various pathogens. This review covers the incidence, pathogenesis, measles variants, clinical presentations, secondary infections, elimination of measles virus on a global scale, and especially the immune responses related to measles infection.

Open Access Status

This publication may be available as open access

Volume

58

Issue

5

Article Number

680

Funding Sponsor

University of Southern Maine

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Link to publisher version (DOI)

http://dx.doi.org/10.3390/medicina58050680