A novel and unexpected one pot synthesis of pyrrolo[1,2-a]quinolines
Publication Name
Tetrahedron Letters
Abstract
A new low temperature route to pyrrolo[1,2-a]quinolines bearing ester groups in the 5-position is reported. The reaction mechanism was found to depend on the reaction temperature. At low temperatures it is proposed the reaction proceeds though an addition-intramolecular SNAr-elimination pathway. This method should find wider use as it avoids high boiling point solvents and affords compatibility with thermosensitive substrates.
Open Access Status
This publication is not available as open access
Article Number
153794
Funding Sponsor
University of Wollongong