Effect of Robot-Assisted Training on EEG-Derived Movement-Related Cortical Potentials for Post-Stroke Rehabilitation-A Case Series Study
Publication Name
IEEE Access
Abstract
This paper deploys movement-related cortical potential (MRCP), an electroencephalogram (EEG)-derived time-domain pattern, to assess the effect of robot-assisted motor training in seven post-stroke patients with hand impairment. Patients are divided into two groups of four subjects with supratentorial lesions and a group of three subjects with infratentorial lesions. Both groups participate in multiple-session motor training for their affected hand with an AMADEO rehabilitation robot. During pre- and post-training periods, three assessment procedures which include EEG signals derived from eight specific electrodes, hand-kinematic parameters, and clinical tests are performed. After four weeks of training, the negative peak of the MRCP signals shows a decrease across all electrodes and reaches significance in seven out of the eight electrodes for the first group according to paired t-test ( $p < 0.05$ ). Whereas for the second group, the MRCP signal shows a decrease in its negative peak across all electrodes and reaches significance in two of the eight electrodes (paired t-test, $p < 0.05$ ) after eight weeks. Moreover, these MRCP changes show a positive association with improvements in kinematic parameters and clinical test results for both groups. Hence, this study shows that improvement of clinical outcomes in robot-assisted training is associated with a reduction in the amplitude of the MRCP signal. Furthermore, infratentorial stroke patients show a slower clinical improvement and require longer rehabilitation to produce significant changes in MRCP compared to subjects with supratentorial stroke.
Open Access Status
This publication may be available as open access
Volume
9
First Page
154143
Last Page
154155