Silver nanoparticles as potential antiviral agents

Publication Name

Pharmaceutics

Abstract

Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology. Emerging viral infections are creating severe hazards to public health worldwide, recently, COVID-19 has caused mass human casualties with significant economic impacts. Interestingly, silver nanoparti-cles (AgNPs) exhibited the potential to destroy viruses, bacteria, and fungi using various methods. However, developing safe and effective antiviral drugs is challenging, as viruses use host cells for replication. Designing drugs that do not harm host cells while targeting viruses is complicated. In recent years, the impact of AgNPs on viruses has been evaluated. Here, we discuss the potential role of silver nanoparticles as antiviral agents. In this review, we focus on the properties of AgNPs such as their characterization methods, antiviral activity, mechanisms, applications, and toxicity.

Open Access Status

This publication may be available as open access

Volume

13

Issue

12

Article Number

2034

Funding Number

2017R1A6A1A03015642

Funding Sponsor

Kortney Rose Foundation

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Link to publisher version (DOI)

http://dx.doi.org/10.3390/pharmaceutics13122034