Radioactive beams for ion therapy: Monte Carlo simulations and experimental verifications

Publication Name

Monte Carlo in Heavy Charged Particle Therapy: New Challenges in Ion Therapy

Abstract

Cancer is a leading cause of death worldwide with over 19 million new cases and 10 million deaths expected in 2020 [Hyuna et al. 22]. The precision of heavy ion therapy makes it particularly useful for treating deeply situated tumors while minimising damage to adjacent healthy tissue. However, due to the steep dose gradients, any deviation between the treatment plan and the delivered dose distribution can result in significant adverse effects on normal tissue, particularly if the treatment region is in the proximity of an organ at risk (OAR). Accurate and, ideally, real-time measurement of spatial dose distribution during irradiation would provide a mechanism for closed-loop control over the treatment process, minimising errors between the treatment plan and the actual delivered dose.

Open Access Status

This publication is not available as open access

First Page

110

Last Page

119

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Link to publisher version (DOI)

http://dx.doi.org/10.1201/9781003023920-8