A Case of Non–Small-cell Lung Cancer in a Patient With Neurofibromatosis Type 1

RIS ID

142095

Publication Details

O'Neill, R., Mohd Zaki, N., Grant, C., Napaki, S. & Brungs, D. (2020). A Case of Non–Small-cell Lung Cancer in a Patient With Neurofibromatosis Type 1. Clinical Lung Cancer, 21 (4), E261-E264.

Abstract

Von Recklinghausen neurofibromatosis type 1 (NF-1) is the most common inherited syndrome predisposing to neoplasia; however, the disease itself has not been commonly associated with lung cancer, with neural crest-derived tumors the most common in the NF-1 population. In addition, patients with NF-1 can develop pulmonary disease that is distinct from malignancy; the most common being diffuse interstitial fibrosis and bullae formation. We report a rare case of metastatic none small-cell lung carcinoma(NSCLC) in a patient with NF-1.

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Link to publisher version (DOI)

http://dx.doi.org/10.1016/j.cllc.2020.02.004