Title

A new secoiridoid glycoside and other constituents from the roots and flowers of Fagraea fragrans Roxb. (Gentianaceae)

RIS ID

143284

Publication Details

Sangsopha, W., Lekphrom, R., Schevenels, F., Byatt, B., Pyne, S., Sridadom, N. & Sawanyawisuth, K. (2020). A new secoiridoid glycoside and other constituents from the roots and flowers of Fagraea fragrans Roxb. (Gentianaceae). Natural Product Research,

Abstract

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. A new secoiridoid glycoside, 3’-O-p-trans-coumaroylsweroside (1), together with twenty-nine compounds (2–30), were isolated from the roots and flowers of Fagraea fragrans Roxb. (Gentianaceae). Their structures were identified by analysis of mass spectrometric and NMR spectroscopic data. Compounds 2, 4, 6, 11 and 13–15 showed weak to moderate cytotoxicity against cholangiocarcinoma cancer cells lines (KKU-213, KKU-055 and KKU-214). We report the first phytochemical investigation of the roots and flowers of F. fragrans, as only the essential oil of the latter has been investigated.

Please refer to publisher version or contact your library.

Share

COinS
 

Link to publisher version (DOI)

http://dx.doi.org/10.1080/14786419.2020.1749611