Bio-ink for on-demand printing of living cells

Authors

Cameron J. Ferris, University of WollongongFollow
Kerry J. Gilmore, University of WollongongFollow
Stephen Beirne, University of WollongongFollow
Donald McCallum, University of WollongongFollow
Gordon G. Wallace, University of WollongongFollow
Marc in het Panhuis, University of WollongongFollow

RIS ID

78131

Publication Details

Ferris, C. J., Gilmore, K. J., Beirne, S., McCallum, D., Wallace, G. G. & in het Panhuis, M. (2013). Bio-ink for on-demand printing of living cells. Biomaterials Science, 1 (2), 224-230.

Abstract

Drop-on-demand bioprinting allows the controlled placement of living cells, and will benefit research in the fields of tissue engineering, drug screening and toxicology. We show that a bio-ink based on a novel microgel suspension in a surfactant-containing tissue culture medium can be used to reproducibly print several different cell types, from two different commercially available drop-on-demand printing systems, over long printing periods. The bio-ink maintains a stable cell suspension, preventing the settling and aggregation of cells that usually impedes cell printing, whilst meeting the stringent fluid property requirements needed to enable printing even from many-nozzle commercial inkjet print heads. This innovation in printing technology may pave the way for the biofabrication of multi-cellular structures and functional tissue.

Grant Number

ARC/LX0989950

Grant Number

ARC/CE0561616

Additional Grant Number

http://purl.org/au-research/grants/ARC/FL110100196, http://purl.org/au-research/grants/ARC/FT0990846