Sequential 1,4- and 1,2-addition reactions to α,β-unsaturated N-acyliminium ions: a new strategy for the synthesis of spiro and bridged heterocycles

Authors

Arife Yazici, University of WollongongFollow
Stephen G. Pyne, University of WollongongFollow

RIS ID

85095

Publication Details

Yazici, A. & Pyne, S. G. (2013). Sequential 1,4- and 1,2-addition reactions to α,β-unsaturated N-acyliminium ions: a new strategy for the synthesis of spiro and bridged heterocycles. Organic Letters, 15 (22), 5878-5881.

Abstract

Novel bicyclic and tetracyclic spirocycles and tricyclic bridged heterocyclic systems can be readily prepared from sequential 1,4- and 1,2-addition reactions of latent bis-nucleophiles to α,β-unsaturated N-acyliminium ions.