The genomic island SGII, containing the multiple antibiotic resistance region of Salmonella enterica Serovar Typhimurium DT104 or variants of it, is widely distributed in other S-enterica serovars

Authors

Renee Levings, University of Wollongong
Diane Lightfoot, University of Melbourne
Sally R. Partridge, Macquarie University
Ruth M. Hall, University of Sydney
Steven P. Djordjevic, Elizabeth Macarthur Agricultural Institute

RIS ID

15104

Publication Details

Levings, R., Lightfoot, D., Partridge, S., Hall, R. & Djordjevic, S. (2005). The genomic island SGII, containing the multiple antibiotic resistance region of Salmonella enterica Serovar Typhimurium DT104 or variants of it, is widely distributed in other S-enterica serovars. Journal of Bacteriology, 187 (13), 4401-4409.

Abstract

The global dissemination of the multiply-antibiotic-resistant Salmonella entericaserovar Typhimurium DT104 clone with the resistance genes located in a class 1 integron, here designated In104, within genomic island SGI1 is a significant public health issue. Here, we have shown that SGI1 and variants of it carrying different combinations of resistance genes are found in several Salmonella enterica serovars. These are serovars Cerro, Derby, Dusseldorf, Infantis, Kiambu, and Paratyphi B dT⁺ isolated from human infections and serovar Emek from sewage effluent. Two new variants, SGI1-I and SGI1-J, both of which include thedfrA1-orfC cassette array, were identified.