Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of β-hydroxyalkynes and o-alkynylphenols and anilines

Authors

Nalivela K. Swamy, University of Wollongong
Arife Yazici, University of WollongongFollow
Stephen G. Pyne, University of WollongongFollow

RIS ID

33689

Publication Details

Swamy, N. K., Yazici, A. & Pyne, S. G. (2010). Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of β-hydroxyalkynes and o-alkynylphenols and anilines. The Journal of Organic Chemistry, 75 (10), 3412-3419.

Abstract

The CuX (X = I, Br, Cl, CN)-mediated cyclization-halogenation and cyclization-cyanation reactions of β-hydroxyalkynes and o-alkynylphenol and -aniline derivatives give rise to 3-halo- and 3-cyanofuro[3,2-b]pyrroles, 3-iodo-, 3-bromo-, and 3-cyanobenzofurans, and 3-cyanoindoles, respectively. © 2010 American Chemical Society.