Sensitive and selective dopamine determination in human serum with inkjet printed Nafion/MWCNT chips

RIS ID

87199

Publication Details

Zhao, J., Yu, Y., Weng, B., Zhang, W., Harris, A. T., Minett, A. I., Yue, Z., Huang, X. & Chen, J. (2013). Sensitive and selective dopamine determination in human serum with inkjet printed Nafion/MWCNT chips. Electrochemistry Communications, 37 32-35.

Abstract

An inkjet printed Nafion/MWCNT chip was developed for rapid dopamine determination in undiluted human serum. A well-dispersed Nafion/MWCNT composite ink was investigated with homogeneous double layers which increased the efficiency of dopamine detection, where direct electron exchange was achieved, producing a measurable current change at the underlying sensor electrode. This platform successfully demonstrated direct detection of DA concentrations (0.1 mu M to 10 mu M, R = 0.999) in real human serum samples using DPV and amperometry methods. This direct measurement of DA in serum samples without pretreatment and dilution is reported for the first time in a Nafion/MWCNT system.

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Link to publisher version (DOI)

http://dx.doi.org/10.1016/j.elecom.2013.10.007