Vacancy engineering of Cu2-: XSe nanoparticles with tunable LSPR and magnetism for dual-modal imaging guided photothermal therapy of cancer

Authors

Shaohua Zhang, University of WollongongFollow
Qian Huang, Soochow University, China
Lijuan Zhang, University of WollongongFollow
Hao Zhang, Soochow University, China
Yaobao Han, Soochow University, China
Qiao Sun, Soochow University, ChinaFollow
Zhenxiang Cheng, University of WollongongFollow
Huizhu Qin, Universtiy Nantong
Shi Xue Dou, University of WollongongFollow
Zhen Li, University of WollongongFollow

RIS ID

122069

Publication Details

Zhang, S., Huang, Q., Zhang, L., Zhang, H., Han, Y., Sun, Q., Cheng, Z., Qin, H., Dou, S. & Li, Z. (2018). Vacancy engineering of Cu2-: XSe nanoparticles with tunable LSPR and magnetism for dual-modal imaging guided photothermal therapy of cancer. Nanoscale, 10 (7), 3130-3143.

Abstract

The vacancies in the semiconductor nanocrystals not only induce unique properties, but also provide spaces for engineering them with multifunctions by the introduction of other elements. Herein, the vacancy of Cu 2-x Se nanoparticles was tuned by doping with magnetic ferric ions (Fe 3+ ) at room temperature, and the position and intensity of the near-infrared localized surface plasmon resonance (LSPR) in the resultant nanostructure can be finely controlled by altering the feeding amount of Fe 3+ ions. The results of the density-functional theory (DFT) calculations show that both doping and replacement reactions are favourable. Owing to its tunable near-infrared absorption and magnetic property, the obtained hybrid nanostructure was demonstrated to be a novel nanotheranostic agent for effective deep-tissue photoacoustic imaging, magnetic resonance imaging, and photothermal therapy of cancer.