Characterization of intermolecular and intramolecular interactions with the atomic force microscope

Authors

Gil U. Lee, University College Dublin
Krasimir Ivanov, University College Dublin
Devrim Kilinc, University College Dublin
Elena Martines, University College Dublin
Agata Blasiak, University College Dublin
Peng Li, Harbin Institute of Technology
Michael J. Higgins, University of WollongongFollow

RIS ID

94863

Publication Details

Lee, G. U., Ivanov, K., Kilinc, D., Martines, E., Blasiak, A., Li, P. & Higgins, M. J. (2014). Characterization of intermolecular and intramolecular interactions with the atomic force microscope. In C. P. Neu & G. M. Genin (Eds.), Handbook of Imaging in Biological Mechanics (pp. 445-456). Boca Raton, United States: CRC Press.

Link to publisher version (URL)

CRC Press

Abstract

The atomic force microscope (AFM) is a powerful nanoscale instrument that is capable of simultaneously imaging biomolecules and measuring the forces between biomolecules attached to the probe and the surface. In this review, we provide an introduction to the experimental and theoretical considerations that are involved in studying single molecular interactions with the AFM.