New integron-associated gene cassette encoding a 3-N-aminoglycoside acetyltransferase

Authors

Renee Levings, Elizabeth Macarthur Agricultural Institute
S. R. Partridge, Macquarie University
Diane Lightfoot, University of Melbourne
Ruth M. Hall, University of Sydney
Steven P. Djordjevic, Elizabeth Macarthur Agricultural Institute

RIS ID

19299

Publication Details

Levings, R., Partridge, S., Lightfoot, D., Hall, R. & Djordjevic, S. (2005). New integron-associated gene cassette encoding a 3-N-aminoglycoside acetyltransferase. Antimicrobial Agents and Chemotherapy, 49 1238-1241.

Abstract

A fifth gene cassette containing an aacC gene, aacCA5, was found in an aacCA5-aadA7 cassette array in a class 1 integron isolated from a multiply drug resistantSalmonella enterica serovar Kentucky strain. The AacC-A5 or AAC(3)-Ie acetyltransferase encoded by aacCA5 is related to other AAC(3)-I enzymes and confers resistance to gentamicin.