Title
Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain
Document Type
Conference Paper
Abstract
Olanzapine is widely used in treating multiple domains of schizophrenia symptoms through its binding profile to various neurotransmitter receptors including a high antagonistic affinity to serotonergic 5-HT2A receptors (5-HT2AR). On the other hand, antagonistic affinity of olanzapine to histamine H1 receptors is a main indicator of its weight gain/obesity side effects.
RIS ID
64910
COinS
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Publication Details
Lian, J., Huang, X., Pai, N. & Deng, C. (2012). Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain. ANS 2012: Australian Neuroscience Society 31st Annual meeting (p. 97). Australia: ANS.