Title

Molecular systems for improving gene mutation correction in muscle disease

RIS ID

45870

Publication Details

Kapsa, R. M., Gasser, G., Razal, J., Quigley, A., Joshi, T., Moulton, S., Cook, M. J., Spiccia, L., Officer, D., Clark, G. M. & Wallace, G. G. (2011). Molecular systems for improving gene mutation correction in muscle disease. Journal of Gene Medicine, 13 (7-8), 437-438.

Abstract

Targeted corrective gene conversion (TCGC) holds much promise as a future therapy for many hereditary diseases in humans, but there still remain significant impediments to effective mutation correction and it is clear that significant work remains to improve TCGC to levels where it can be considered for translation to the clinical setting.

Grant Number

ARC/FF0669110, ARC/DP0987503