Doctor of Philosophy
School of Medicine
Consumption of n-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) is associated with higher n-3 LCPUFA status in the circulation, which has in turn has been associated with a number of health benefits in humans. n-3 LCPUFA cardiovascular health benefits are well known and there is emerging evidence for mental health benefits. Limited studies have indicated that there is a positive correlation between an improvement of Ultra-High-Risk (UHR) of developing psychosis symptoms and the intake of n-3 LCPUFA; however there is a need for further studies involving larger randomized-controlled studies since the previous work was conducted with low numbers. These studies have also shown that people classified as UHR of developing psychosis have reduced n-3 PUFA, n-6 PUFA and n-3 index. What is unknown is the molecular phospholipid data and how that data may relate to developing psychosis and also how this is affected by n-3 LCPUFA supplementation.
Alqarni, Ayedh Saad, Investigation of alteration in erythrocyte lipids in people at ultra high risk of developing psychosis, Doctor of Philosophy thesis, School of Medicine, University of Wollongong, 2018. https://ro.uow.edu.au/theses1/471
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