Year

2018

Degree Name

Doctor of Philosophy

Department

School of Chemistry

Abstract

The ring-opening process of cyclopropane derivatives is prominent in biological processes and synthetic methodology. The reactivity of bifunctional three-membered rings is attributed to the ring-strain and the attached functional groups which can stabilise their ring-opened counterparts. This thesis reports the use of cyclopropane derivatives in synthetic methodology and syntheses of prodrugs.

FoR codes (2008)

0304 MEDICINAL AND BIOMOLECULAR CHEMISTRY, 0305 ORGANIC CHEMISTRY, 0601 BIOCHEMISTRY AND CELL BIOLOGY

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Unless otherwise indicated, the views expressed in this thesis are those of the author and do not necessarily represent the views of the University of Wollongong.