International consensus statement on obstructive sleep apnea

Authors

Jolie L. Chang, University of California, San Francisco
Andrew N. Goldberg, University of California, San Francisco
Jeremiah A. Alt, The University of Utah
Lisa Ashbrook, University of California, San Francisco
Dennis Auckley, Case Western Reserve University
Indu Ayappa, Icahn School of Medicine at Mount Sinai
Hira Bakhtiar, Norwalk Hospital
José E. Barrera, Uniformed Services University of the Health Sciences
Bethany L. Bartley, Harvard Medical School
Martha E. Billings, University of Washington
Maurits S. Boon, Thomas Jefferson University
Pien Bosschieter, Academisch Centrum Tandheelkunde Amsterdam
Itzhak Braverman, Hillel Yaffe Medical Center
Kara Brodie, University of California, San Francisco
Cristina Cabrera-Muffly, University of Colorado School of Medicine
Ray Caesar, Stone Oak Medical Building
Michel B. Cahali, Universidade de São Paulo
Yi Cai, University of California, San Francisco
Michelle Cao, Stanford University
Robson Capasso, Stanford University
Sean M. Caples, Mayo Clinic
Lana M. Chahine, University of Pittsburgh
Corissa P. Chang, University of Pennsylvania
Katherine W. Chang, Washington University in St. Louis
Nilika Chaudhary, PENDING
Crystal S.J. Cheong, National University Hospital
Susmita Chowdhuri, Wayne State University
Peter A. Cistulli, Faculty of Medicine and Health
David Claman, University of California, San Francisco

Publication Name

International Forum of Allergy and Rhinology

Abstract

Background: Evaluation and interpretation of the literature on obstructive sleep apnea is needed to consolidate and summarize key factors important for clinical management of the OSA adult patient. Toward this goal, an international collaborative of multidisciplinary experts in sleep apnea evaluation and treatment have produced the International Consensus statement on Obstructive Sleep Apnea (ICS:OSA). Methods: Using previously defined methodology, focal topics in OSA were assigned as literature review (LR), evidence-based review (EBR), or evidence-based review with recommendations (EBR-R) formats. Each topic incorporated the available and relevant evidence which was summarized and graded on study quality. Each topic and section underwent iterative review and the ICS:OSA was created and reviewed by all authors for consensus. Results: The ICS:OSA addresses OSA syndrome definitions, pathophysiology, epidemiology, risk factors for disease, screening methods, diagnostic testing types, multiple treatment modalities, and effects of OSA and treatment on the multiple comorbidities. Specific focus on outcomes with positive airway pressure (PAP) and surgical treatments were evaluated. Conclusion: This review of the literature in OSA consolidates the available knowledge and identifies the limitations of the current evidence. This effort aims to highlight the basis of OSA evidence-based practice and identify future research needs. Knowledge gaps and opportunities for improvement include improving the metrics of OSA disease, determining the optimal OSA screening paradigms, developing strategies for PAP adherence and longitudinal care, enhancing selection of PAP alternatives and surgery, understanding health risk outcomes, and translating evidence into individualized approaches to therapy. This article is protected by copyright. All rights reserved.

Open Access Status

This publication is not available as open access