Title

Is it time to stop using statistical significance?

Publication Name

Australian Prescriber

Abstract

The important first step in the critical appraisal of a randomised trial is not an evaluation of the statistical analyses. The most important aspect to consider when reviewing a study of a new drug is the appropriateness and quality of the trial design and methods. The next most important aspect is the effect size of different treatments and its clinical significance. Rather than reporting statistical significance, studies should report the difference between treatments and its precision. Over-reliance on statistical significance and p values may lead to incorrect conclusions. Trial reports about drugs should therefore avoid the term statistical significance and quote p values with caution.

Open Access Status

This publication may be available as open access

Volume

44

Issue

1

First Page

16

Last Page

18

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Link to publisher version (DOI)

http://dx.doi.org/10.18773/austprescr.2020.074