Title
Synthesis of syn-and enantioenriched anti-β-amino alcohols by highly diastereoselective borono-Mannich allylation reactions
Publication Name
Chemical Communications
Abstract
A highly diastereoselective method for the synthesis of syn-β-amino alcohols and enantioenriched anti-β-amino alcohols has been developed involving α-hydroxyl aldehydes and chiral α-phenylaminoxyaldehydes or α-benzoyloxyaldehydes, respectively in Petasis borono-Mannich allylation reactions. This study broadens the scope and utility of the Petasis reaction to include pinacol allylboronate and highlights its unique reactivity and stereochemical outcomes.
Open Access Status
This publication is not available as open access
Volume
58
Issue
13
First Page
2220
Last Page
2223
Funding Sponsor
University of Wollongong