Title

A new secoiridoid glycoside and other constituents from the roots and flowers of Fagraea fragrans Roxb. (Gentianaceae)

Publication Name

Natural Product Research

Abstract

A new secoiridoid glycoside, 3’-O-p-trans-coumaroylsweroside (1), together with twenty-nine compounds (2–30), were isolated from the roots and flowers of Fagraea fragrans Roxb. (Gentianaceae). Their structures were identified by analysis of mass spectrometric and NMR spectroscopic data. Compounds 2, 4, 6, 11 and 13–15 showed weak to moderate cytotoxicity against cholangiocarcinoma cancer cells lines (KKU-213, KKU-055 and KKU-214). We report the first phytochemical investigation of the roots and flowers of F. fragrans, as only the essential oil of the latter has been investigated.

Open Access Status

This publication is not available as open access

Volume

35

Issue

21

First Page

3908

Last Page

3917

Funding Sponsor

Khon Kaen University

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Link to publisher version (DOI)

http://dx.doi.org/10.1080/14786419.2020.1749611