The phytochemical investigation of the leaf extract of Uvaria cherrevensis (Annonaceae) yielded three new cyclohexene (9Z)-octadec-9-enyl ethers, cherrevenols M-O (1-3), and a known fatty ester derivative (4). The structures of the isolated compounds were elucidated by spectroscopic and computer-aided molecular modelling methods. Ozone Induced Dissociation (OzID) mass spectrometry was employed to determine the C-9 position of the side chain olefinic double bonds, while 13 C NMR spectroscopy indicated their (Z)-configurations. All isolated compounds were evaluated for their antimalarial and cytotoxic activities; all were inactive.
Publication Details Citation
Auranwiwat, C., Maccarone, A. T., Carroll, A., Rattanajak, R., Kamchonwongpaisan, S., Blanksby, S. J., Pyne, S. G., & Limtharakul, T. (2019). Structure elucidation of cyclohexene (9Z)-octadec-9-enyl ethers isolated from the leaves of Uvaria cherrevensis (Annonaceae). Faculty of Science, Medicine and Health - Papers: Part B. https://doi.org/10.1016/j.tet.2019.03.004. Retrieved from https://ro.uow.edu.au/smhpapers1/603