Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis

Authors

Chiramet Auranwiwat, Chiang Mai University, University of Wollongong
Puttandon Wongsomboon, Chiang Mai University
Thanaphat Thaima, University of WollongongFollow
Roonglawan Rattanajak, Thailand Science Park
Sumalee Kamchonwongpaisan, Thailand Science Park
Anthony C. Willis, Australian National University
Surat Laphookhieo, Mae Fah Luang UniversityFollow
Stephen G. Pyne, University of WollongongFollow
Thunwadee Limtharakul, Chiang Mai University

RIS ID

133060

Publication Details

Auranwiwat, C., Wongsomboon, P., Thaima, T., Rattanajak, R., Kamchonwongpaisan, S., Willis, A. C., Laphookhieo, S., Pyne, S. G. & Limtharakul, T. (2019). Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis. Journal of Natural Products, 82 (1), 101-110.

Abstract

The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A-K (1-11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known compounds (13-21) were also isolated. Three of the isolated compounds are chlorinated polyoxygenated cyclohexenes. The structures of these compounds were determined using spectroscopic methods and, in some cases (compounds 2, 6, 8, and 10), single-crystal X-ray crystallographic structural analysis or chemical correlation (compounds 6 and 7). Compounds 6 and 7 were both isolated as scalemic mixtures (ee 23-24%).