A new 2-arylbenzofuran, spathobenzofuran (1), together with ten known compounds including a 2-arylbenzofuran, three pterocarpans and six isoflavones were isolated from the acetone crude extract of the stems of Spatholobus parviflorus. All compounds were characterised by spectroscopic methods. Compound 4 was active (MIC 8 µg/mL) against Gram-negative Pseudomonas aeruginosa TISTR 781 while compound 2 had modest activity against Gram-positive Staphylococcus aureus TISTR 1466 with a MIC value of 16 µg/mL. All isolated compounds showed no cytotoxicity against Vero and KB cells.
Publication Details Citation
Promchai, T., Janhom, P., Maneerat, W., Rattanajak, R., Kamchonwongpaisan, S., Pyne, S. G., & Limtharakul, T. (2018). Antibacterial and cytotoxic activities of phenolic constituents from the stem extracts of Spatholobus parviflorus. Faculty of Science, Medicine and Health - Papers: Part B. https://doi.org/10.1080/14786419.2018.1512990. Retrieved from https://ro.uow.edu.au/smhpapers1/491
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