RIS ID

132445

Publication Details

Promchai, T., Janhom, P., Maneerat, W., Rattanajak, R., Kamchonwongpaisan, S., Pyne, S. G. & Limtharakul, T. (2018). Antibacterial and cytotoxic activities of phenolic constituents from the stem extracts of Spatholobus parviflorus. Natural Product Research, Online First 1-5.

Abstract

A new 2-arylbenzofuran, spathobenzofuran (1), together with ten known compounds including a 2-arylbenzofuran, three pterocarpans and six isoflavones were isolated from the acetone crude extract of the stems of Spatholobus parviflorus. All compounds were characterised by spectroscopic methods. Compound 4 was active (MIC 8 µg/mL) against Gram-negative Pseudomonas aeruginosa TISTR 781 while compound 2 had modest activity against Gram-positive Staphylococcus aureus TISTR 1466 with a MIC value of 16 µg/mL. All isolated compounds showed no cytotoxicity against Vero and KB cells.

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Link to publisher version (DOI)

http://dx.doi.org/10.1080/14786419.2018.1512990