The phytochemical investigation of the leaf extracts of Uvaria hamiltonii (Annonaceae) led to the isolation and identification of ten compounds including a new seco-cyclohexene (1) together with nine known compounds (2-10). Their structures were elucidated by intensive analysis by spectroscopic methods and comparisons of their spectroscopic data with those of compounds reported in the literature. Compounds 2, 8, and 9 showed potent α-glucosidase inhibitory activity with the IC50 values ranging from 2.6-7.1 µM.
Publication Details Citation
Meesakul, P., Pyne, S. G., & Laphookhieo, S. (2018). Potent α-glucosidase inhibitory activity of compounds isolated from the leaf extracts of Uvaria hamiltonii. Faculty of Science, Medicine and Health - Papers: Part B. https://doi.org/10.1080/14786419.2018.1538996. Retrieved from https://ro.uow.edu.au/smhpapers1/490
Available for download on Monday, December 23, 2019