Herein we report the formation of pyrrolines and tetrahydropyridines from the cyclisation reactions of β-amino allenes by both AuI and AgI catalysts in yields ranging from 5 to 70 %. AuI catalysts favour a 5-endo-dig cyclisation before rapid rearrangement to the 5-exo-dig product, while AgI favours a 6-endo-trig cyclisation. We also report the first known Ag2O catalysed cyclisation reaction of an allene which occurred in good yield (61 %).
Publication Details Citation
Joyce, L., Willis, A. C., Hyland, C. J., & Pyne, S. G. (2018). Gold- and Silver-Catalysed Cyclisation Reactions of β-Amino Allenes. Faculty of Science, Medicine and Health - Papers: Part B. https://doi.org/10.1071/CH18197. Retrieved from https://ro.uow.edu.au/smhpapers1/190