Title

68Ga-Prostate-Specific Membrane Antigen Uptake in Cerebral Tuberculosis

RIS ID

141469

Publication Details

Wong, V., Shen, L., Nasser, E., Adams, D. N. & Mansberg, R. (2020). 68Ga-Prostate-Specific Membrane Antigen Uptake in Cerebral Tuberculosis. Clinical Nuclear Medicine, 45 (3), 238-240.

Abstract

A 71-year-old man with a history of high-risk prostate adenocarcinoma (Gleason score 4 + 5 = 9) treated with brachytherapy in 2016 was referred for a 68Ga–prostate-specific membrane antigen (PSMA)–HBED–CC PET/CT scan for suspected cancer recurrence on a background of slowly rising serum prostate-specific antigen (0.95 ng/mL; reference, <0.2 ng/mL). This revealed PSMA-avid dura-based hyperdense lesions in the brain, suggestive of cerebral metastases. Biopsy demonstrated the presence of acid-fast bacilli, and with further clinical and microbiological testing, a diagnosis of PSMA-avid cerebral tuberculous mycobacterium infection was made.

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Link to publisher version (DOI)

http://dx.doi.org/10.1097/RLU.0000000000002910