RIS ID

140072

Publication Details

Suthiphasilp, V., Maneerat, W., Andersen, R. J., Phukhatmuen, P., Pyne, S. G. & Laphookhieo, S. (2019). Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum. Journal of Natural Products, 82 (11), 3176-3180.

Abstract

Five new aristolactam alkaloids (1-5), dasymaschalolactams A-E, and the first isolation of dasymaschalolactone (17) as a natural product, together with 19 known compounds (6-16 and 18-25) were isolated from the twig extract of Dasymaschalon dasymaschalum. Their structures were elucidated by spectroscopic methods as well as comparisons made from the literature. Compounds 20 and 21 showed α-glucosidase inhibitory activities with IC50 values of 4.5 and 24.7 μM, respectively.

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Link to publisher version (DOI)

http://dx.doi.org/10.1021/acs.jnatprod.9b00506