Supraglottitis due to group B streptococcus in an adult with IgG4 and C2 deficiency: a case report and review of the literature

Authors

Vinayak Nagaraja, Prince of Wales Hospital
Thomas E. Stewart, Wollongong Hospital
Stuart Mackay, Wollongong HospitalFollow
Derek W. Glenn, St George Hospital
Denis Wakefield, University of New South Wales
Craig S. Boutlis, University of WollongongFollow

RIS ID

99731

Publication Details

Nagaraja, V., Stewart, T. E., Mackay, S. G., Glenn, D. W., Wakefield, D. & Boutlis, C. S. (2015). Supraglottitis due to group B streptococcus in an adult with IgG4 and C2 deficiency: a case report and review of the literature. The Laryngoscope, 125 (4), 852-855.

Abstract

Acute supraglottitis is a medical emergency as it can rapidly lead to airway compromise. With routine pediatric immunization for Hemophilus influenzae serotype b, supraglottitis is now more prevalent in adults, with a shift in the causative organisms and a change in the natural history of this disease. Here, we present a case of supraglottitis due to group B streptococcus that occurred in an adult with previously undetected immunoglobulin 4 (IgG4) and complement protein C2 deficiency.