RIS ID
96775
Abstract
Increasing numbers of biological applications of fullerenyl amino acids and their derivatives encouraged us to synthesise [60]fullerenyldihydropyrrole peptides, prepared from the coupling of mono- and bis[60]fullerenyldihydropyrrolecarboxylic acids 4, 5 and 41 with presynthesised peptides 13, 16, 24, 28, 29 and 46. The resulting hydrophobic scaffolded di- and tetra-cationic derivatives were tested against Staphylococcus aureus NCTC 6571 and Escherichia coli NCTC 10418. The synthesis, characterisation and biological results are discussed in this paper.
Grant Number
NHMRC/APP1051105
Publication Details
Jennepalli, S., Hammer, K. A., Riley, T. V., Pyne, S. G. & Keller, P. A. (2015). Synthesis of mono and bis[60]fullerene-based dicationic peptoids. European Journal of Organic Chemistry, 2015 (1), 195-201.