Cell surface antigens of Mycoplasma species bovine group 7 bind and activate plasminogen

Authors

Kylie Bower, University of Wollongong
Steven Djordjevic, NSW Agriculture
Nicholas M Andronicos, University of Wollongong
Marie Ranson, University of WollongongFollow

RIS ID

9941

Publication Details

Bower, K., Djordjevic, S. P., Andronicos, N. M. & Ranson, M. (2003). Cell surface antigens of Mycoplasma species bovine group 7 bind and activate plasminogen. Infection and Immunity, 71 (8), 4823-4827.

Abstract

Mycoplasma species bovine group 7 bound plasminogen at the cell surface in a lysine-dependent manner. Cell-bound plasminogen was rapidly activated to plasmin by exogenous urokinase, and this activity was associated with plasminogen binding capacity. Binding assays using plasminogen modified with a trifunctional cross-linking agent revealed several binding proteins.