Synthesis of (+/-)epipentenomycin I and III

Authors

Weerachai Phutdhawong, Mae Jo University
Stephen G. Pyne, University of WollongongFollow
Apiwat Baramee, Chiang Mai University
Duang Buddhasukh, Chiang Mai University
Brian W. Skelton, University of Western Australia
Allan H. White, University of Western Australia

RIS ID

8298

Publication Details

Pyne, S. G., Phutdhawong, W., Baramee, A., Buddhasukh, D., Skelton, B. W. & White, A. H. (2002). Synthesis of (+/-)epipentenomycin I and III. Tetrahedron Letters, 43 6047-6049.

Abstract

A synthesis of (±) epipentenomycin I and III is reported from a regioselective epoxidation of racemic 3-hydroxy- and 3-acetoxy-2-methylene-4-cyclopentenone, respectively, with dimethyldioxirane followed by hydrolytic ring-opening of the resulting epoxide.