RIS ID
11489
Abstract
Two new dihydrostemofoline alkaloids, 11(S),12(R)-dihydrostemofoline (3) and stemoburkilline (4), along with stemofoline (1) and 2’-hydroxystemofoline (2) have been isolated from a root extract of Stemona burkillii Prain. The structure and relative configuration of (3) have been determined via spectroscopic data and from comparison with synthetic 11(S),12(S)-dihydrostemofoline (5). The configuration of the exo-cyclic alkene group in (4) is tentively assigned as (E) based upon mechanistic considerations.
Included in
Life Sciences Commons, Physical Sciences and Mathematics Commons, Social and Behavioral Sciences Commons
Publication Details
Mungkornasawakul, P., Pyne, S. G., Lie, W., Ung, A. T., Jatisatienr, A., Issakul, K., Sawatwanich, A. & Supyen, D. (2004). Phytochemical studies on Stemona burkillii Prain: Two new dihydrostemofoline alkaloids. Journal of Natural Products, 67 1740-1743.