Synthesis of (+)-uniflorine A: a structural reassignment and a configurational assignment

Authors

Thunwadee Ritthiwigrom, University of WollongongFollow
Stephen G. Pyne, University of WollongongFollow

RIS ID

25499

Publication Details

Ritthiwigrom, T. and Pyne, S. G. (2008). Synthesis of (+)-uniflorine A: a structural reassignment and a configurational assignment. Organic Letters, 10 (13), 2769-2771.

Abstract

The total synthesis of (+)-uniflorine A has allowed for the structural reassignment and the configurational assignment of the alkaloid (−)-uniflorine A from a 1,2,6,7,8-pentahydroxyindolizidine structure to (−)-(1R,2R,3R,6R,7S,7aR)-1,2,6,7-tetrahydroxy-3-hydroxymethylpyrrolizidine (6-epi-casuarine).