Soluble adhesion molecules and interleukin-2 receptor concentrations in patients with autoimmune chronic hepatitis
To test the hypothesis that elevated serum levels of intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), (s)E-selectin, (s)P-selectin and soluble interleukin-2 receptor (sIL-2R) occur in patients with biochemically inactive autoimmune hepatitis (AICH) compared with controls. Such a finding would suggest continued immune activation, which in the long-term would contribute to the development of cirrhosis in such patients.
Simpson, K. J., Jones, A. L., Forbes, A. Hayes, P. C. (1995). Soluble adhesion molecules and interleukin-2 receptor concentrations in patients with autoimmune chronic hepatitis. European Journal of Gastroenterology and Hepatology, 7 (5), 455-460.