Recent advances in the management of poisoning



Publication Details

Jones, A. L. (2002). Recent advances in the management of poisoning. Therapeutic Drug Monitoring, 24 (1), 150-155.


Self-poisoning is responsible for at least 20% of acute admissions to hospital in the UK (1–2) and represents a significant workload for healthcare Professionals worldwide. The topics in this article have been chosen as they represent significant changes in understanding of clinical toxicology working practices over the last three years. Thus recent advances in the management of poisoning by tricyclic antidepressants, ethylene glycol and methanol, salicylates and carbon monoxide are covered. Tricyclic antidepressant overdoses represent approximately half the poisoned patient workload of Intensive Care Units. Carbon monoxide has been chosen because it is the number one cause of death by poisoning in the UK and the role of hyperbaric oxygen in its management is very controversial.

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