Service and application requirements on network resilience have increased over the past few years. New on-line services such as e-commerce and connection-oriented interactive real-time services require higher network resilience than the more traditional off-line services. Programmable virtual networks promise fast and easy provisioning of new services but no consideration to meet the diverse resilience requirements has been made. This paper discusses issues related to resilience-differentiation in programmable virtual networks. A set of general guidelines is presented that apply to resilience-differentiation in programmable virtual network architectures. A case study is used to illustrate how the proposed guidelines can be met by extending an existing programmable virtual network architecture.