The Illawarra Health and Medical Research Institute is a partnership between the University of Wollongong and the South Eastern Sydney Illawarra Area Health Service. IHMRI's research focuses on health and medical issues that are common in the Illawarra region and is aimed at improving the health and well being of the local community. IHMRI's goal is to foster research collaboration through the IHMRI Research Network, creating a centre of excellence and innovation that represents the focal point of health and medical research in this region.
Papers from 2005
Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARγ ligands, C M Quinn, W Jessup, Jenny Wong, L Kritharides, and A Brown
Phosphorylation of apolipoprotein-E at an atypical protein kinase CK2 PSD/E site in vitro, M. Raftery, R. Campbell, Elias Glaros, Kerry-Anne Rye, G. Halliday, W. Jessup, and Brett Garner
Activity-dependent maintenance and growth of dendrites in adult cortex, Chris Tailby, Layne L. Wright, Andrew B. Metha, and Mike B. Calford
Intravenous anaesthetics inhibit nicotinic acetylcholine receptor-mediated currents and Ca2+ transients in rat intracardiac ganglion neurons, Martin Weber, Leonid Motin, Simon Gaul, Friederike Beker, Rainer H. A Fink, and David J. Adams
Papers from 2004
Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells, David J. Adams and Michael A Hill
Structures of μO-conotoxins from Conus marmoreus: Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons, Norelle L. Daly, Jenny Ekberg, Linda Thomas, David J. Adams, Richard J. Lewis, and David J. Craik
Plasma surfactant protein-B: a novel biomarker in chronic heart failure, C G. De Pasquale, Leonard F. Arnolda, Ian R. Doyle, Phillip E. Aylward, Derek Derek Chew, and Andrew D. Bersten
Two cases of thyroid carcinoma that were not stimulated by recombinant human thyotropin, Barbara Depczynski and Stephen Lillioja
Unique levels of expression of N-methyl-D-aspartate receptor subunits and neuronal nitric oxide synthase in the rostral ventrolateral medulla of the spontaneously hypertensive rat, Mark A. Edwards, Rhonda A. Loxley, Kellysan Powers-Martin, Janusz Lipski, Douglas J. McKitrick, Leonard F. Arnolda, and Jacqueline K. Phillips
Regulation of neuronal voltage-gated sodium channels by the ubiquitin protein ligases Nedd4 and Nedd4-2, Andrew B. Fotia, Jenny Ekberg, David J. Adams, David I. Cook, Philip Poronnik, and Sharad Kumar
Functional maturation of isolated neural progenitor cells from the adult rat hippocampus, Ron C. Hogg, Hiram Chipperfield, K A. Whyte, Mark R. Stafford, Mitchell A. Hansen, Simon M. Cool, Victor Nurcombe, and David J. Adams
Effect of anaesthetic and rat strain on heart rate responses to simulated haemorrhage, Vasyl Holobotovskyy, Leonard F. Arnolda, and Douglas J. McKitrick
Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors, Anna Kloda, John D. Clements, Richard J. Lewis, and David J. Adams
Chemical and functional identification and characterization of novel sulfated α-conotoxins from the cone snail Conus anemone, Marion L. Loughnan, Annette Nicke, Alun Jones, David J. Adams, Paul F. Alewood, and Richard J. Lewis
Expression and function of neuronal nicotinic ACh receptors in rat microvascular endothelial cells, Francesco Mocca, Christine L. Frost, Roberto Berra-Romani, Franco Tanzi, and David J. Adams
The α2δ auxiliary subunit reduces affinity of ω-conotoxins for recombinant N-type (Cav2.2) calcium channels, Jorgen Mould, Takahiro Yasuda, Christina I. Schroeder, Aaron M. Beedle, Clinton J. Doering, Gerald W. Zamponi, David J. Adams, and Richard J. Lewis
Multi-elemental analysis of brain tissue from healthy Wistar rats using sector field inductively coupled plasma mass spectrometry, Mitchell C. Paul, Carl H. Parsons, Mike B. Calford, and Ellak I. von Nagy-Felsobuki
Usefulness of clinical assessment of the carotid pulse in the diagnosis of aortic stenosis, Joseph Selvanayagam, C G. De Pasquale, and Leonard F. Arnolda
Vasomotor responses to decreased venous return: effects of cardiac deafferentation in humans, Cara J. Weisbrod, Leonard F. Arnolda, Douglas J. McKitrick, Gerard O'Driscoll, Kathleen Potter, and Daniel J. Green
Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells, Takahiro Yasuda, Lina Chen, Wendy Barr, John E. Mcrory, Richard J. Lewis, David J. Adams, and Gerald W. Zamponi
Overexpressed Cavβ3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of "ultra-slow" and "closed-state" inactivation, Takahiro Yasuda, Richard J. Lewis, and David J. Adams
Papers from 2003
ω-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals, David J. Adams, Amanda B. Smith, Christina I. Schroeder, Takahiro Yasuda, and Richard J. Lewis
Muscarinic and nicotinic ACh receptor activation differentially mobilize Ca2+ in rat intracardiac ganglion neurons, Friederike Beker, Martin Weber, Rainer H. Fink, and David J. Adams
Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII, Joanne T. Blanchfield, Julie L. Dutton, Ron C. Hogg, Oliver P. Gallagher, David J. Craik, Alun Jones, David J. Adams, Richard J. Lewis, Paul F. Alewood, and Istvan Toth
Topographic plasticity in primary visual cortex is mediated by local corticocortical connections, Mike B. Calford, Layne L. Wright, Andrew B. Metha, and Vivian Taglianetti
Lowering blood pressure in 2003, John Chalmers and Leonard F. Arnolda
Prolonged alveolocapillary barrier damage after acute cardiogenic pulmonary edema, C G. De Pasquale, Leonard F. Arnolda, Ian R. Doyle, Robyn L. Grant, Phillip E. Aylward, and Andrew D. Bersten
Infarct-induced chronic heart failure increases bidirectional protein movement across the alveolocapillary barrier, C G. De Pasquale, Andrew D. Bersten, Ian R. Doyle, Phillip E. Aylward, and Leonard F. Arnolda
α-conotoxins PnIA and [A10L]PnIA stabilize different states of the α7-L247T nicotinic acetylcholine receptor, Ron C. Hogg, Gene Hopping, Paul F. Alewood, David J. Adams, and Daniel Bertrand
Isolation, structure, and activity of GID, a novel α4/7-conotoxin with an extended N-terminal sequence, Annette Nicke, Marion L. Loughnan, Emma L. Millard, Paul F. Alewood, David J. Adams, Norelle L. Daly, David J. Craik, and Richard J. Lewis
Inhibition of the norepinephrine transporter by the venom peptide χ-MrIA: site of action, Na+ dependence, and structure-activity relationship, Iain A. Sharpe, Elka Palant, Christina I. Schroeder, David M. Kaye, David J. Adams, Paul F. Alewood, and Richard J. Lewis
Allosteric α1-adrenoreceptor antagonism by the conopeptide ρ-TIA, Iain A. Sharpe, Linda Thomas, Marion L. Loughnan, Leonid Motin, Elka Palant, Daniel E. Croker, Dianne Alewood, Songhai Chen, Robert M. Graham, Paul F. Alewood, David J. Adams, and Richard J. Lewis
Laminar differences in plasticity in area 17 following retinal lesions in kittens or adult cats, W. J. Waleszczyk, C. Wang, J. M. Young, W. Burke, M. B. Calford, and B. Dreher
Candesartan and hydrochlorothiazide in isolated systolic hypertension, Lindon M. H Wing, Leonard F. Arnolda, Jane Upton, and Danielle Molloy
Dizziness and loss of consciousness: cardiovascular causes, Jeremy J. J. Wright and Leonard F. Arnolda
Papers from 2002
Neural control of the heart: developmental changes in ionic conductances in mammalian intrinsic cardiac neurons, David J. Adams, Alexander A. Harper, and Ron C. Hogg
Inducible nitric oxide synthase and cardiac dysfunction in salt-sensitive hypertension, Leonard F. Arnolda
Laminar differences in plasticity in striate cortex of cats, W Burke, W J. Waleszczyk, C Wang, J M. Young, M B. Calford, and B Dreher
Dynamic representational plasticity in sensory cortex, M B. Calford
Mechanisms for acute changes in sensory maps, Mike B. Calford
A new level of conotoxin diversity, a non-native disulfide bond connectivity in α-conotoxin AuIB reduces structural definition but increases biological activity, Julie L. Dutton, Paramjit S. Bansal, Ron C. Hogg, David J. Adams, Paul F. Alewood, and David J. Craik
Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons, Ron C. Hogg, Richard J. Lewis, and David J. Adams
Neurochemistry of nerve fibers apposing sympathetic preganglionic neurons activated by sustained hypotension, Jane B. Minson, Leonard F. Arnolda, and Ida J. Llewellyn-Smith
Basal nonselective cation permeability in rat cardiac microvascular endothelial cells, Francesco Mocca, Roberto Berra-Romani, Silvana Baruffi, Santina Spaggiari, David J. Adams, Vannic Taglietti, and Franco Tanzi
Solution structure of μ-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels, Katherine J. Nielsen, Michael Watson, David J. Adams, Anna K. Hammarström, Peter W. Gage, Justine M. Hill, David J. Craik, Linda Thomas, Denise Adams, Paul F. Alewood, and Richard J. Lewis
BK channels, baroreflex sensitivity and genetic markers, Jacqueline K. Phillips and Leonard F. Arnolda
Topographic reorganization in area 18 of adult cats following circumscribed monocular retinal lesions in adolescence, J M. Young, W J. Waleszczyk, W Burke, M B. Calford, and B Dreher
Papers from 2001
Time of day and access to food alter water intake in rats after water deprivation, Kooi K. Ang, Douglas J. McKitrick, Paddy Phillips, and Leonard F. Arnolda
Containing the costs of managing hypertension, Leonard F. Arnolda
Metabolic support for the heart?, Leonard F. Arnolda
Coronary artery baroreceptor-mediated changes in arterial pressure: A pilot study in conscious and anaesthetized sheep, J S. Bennetts, Leonard F. Arnolda, H C. Cullen, J L. Knight, R A. Baker, and Douglas J. McKitrick
The synthesis and structure of an n-terminal dodecanoic acid conjugate of α-conotoxin MII, Joanne T. Blanchfield, Julie L. Dutton, Ron C. Hogg, David J. Craik, David J. Adams, Richard J. Lewis, Paul F. Alewood, and Istvan Toth
Neurokinin-1 receptor immunoreactivity in hypotension sensitive sympathetic preganglionic neurons, Kathleen J. Burman, Douglas J. McKitrick, Jane B. Minson, Anais West, Leonard F. Arnolda, and Ida J. Llewellyn-Smith
Limits on short-term plasticity in somatosensory cortex, M B. Calford
Personal frames of reference in professional practice, Anne Cusick
Neurosteroids mediate habituation and tonic inhibition in the auditory midbrain, Anita Disney and Mike B. Calford
Cortical plasticity revealed by circumscribed retinal lesions or artificial scotomas, B Dreher, W Burke, and M B. Calford
Large-conductance calcium-activated potassium channels in neonatal rat intracardiac ganglion neurons, F Franciolini, Ron C. Hogg, L. Catacuzzeno, A Petris, C Trequattrini, and David J. Adams
An ATP-sensitive K+ conductance in dissociated neurones from adult rat intracardiac ganglia, Ron C. Hogg and David J. Adams
Developmental changes in hyperpolarization-activated currents Ih and IK(IR) in isolated rat intracardiac neurons, Ron C. Hogg, Alexander A. Harper, and David J. Adams
Ionic selectivity of native ATP-activated (P2X) receptor channels in dissociated neurones from rat parasympathetic ganglia, Dong-Mei Liu and David J. Adams
Neuropeptide Y mRNA expression in interneurons in rat spinal cord, Jane B. Minson, Ida J. Llewellyn-Smith, and Leonard F. Arnolda
Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter, Iain A. Sharpe, John Gehrmann, Marion L. Loughnan, Linda Thomas, Denise Adams, Ann Atkins, Elka Palant, David J. Craik, David J. Adams, Paul F. Alewood, and Richard J. Lewis
Pre- and postsynaptic actions of ATP on neurotransmission in rat submandibular ganglia, Amanda B. Smith, Mitchell A. Hansen, Dong-Mei Liu, and David J. Adams
Spontaneous and stimulus-evoked intrinsic optical signals in primary auditory cortex of the cat, Matthew W. Spitzer, Michael B. Calford, Janine C. Clarey, John D. Pettigrew, and Anna W. Roe
Papers from 2000
Nitric oxide limits pressor responses to sympathetic activation in rat spinal cord, Leonard F. Arnolda, Douglas J. McKitrick, Ida J. Llewellyn-Smith, and Jane B. Minson
Reorganization of neural circuits in area 17 of the cat following retinal lesions in adolescent kittens, W Burke, W J. Waleszczyk, C Wang, B Dreher, and M B. Calford
Plasticity in adult cat visual cortex (area 17) following circumscribed monocular lesions of all retinal layers, M B. Calford, C Wang, V Taglianetti, W J. Waleszczyk, W Burke, and B Dreher
Substance P preferentially inhibits large conductance nicotinic ACh receptor channels in rat intracardiac ganglion neurons, Javier Cuevas and David J. Adams
Novel ω-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes, Richard J. Lewis, Katherine J. Nielsen, David J. Craik, Marion L. Loughnan, Denise Adams, Iain A. Sharpe, Tudor Luchian, David J. Adams, Trudy Bond, Linda Thomas, Alun Jones, Jodi-Lea Matheson, Roger Drinkwater, Peter R. R. Andrews, and Paul F. Alewood
VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation, Dong-Mei Liu, Javier Cuevas, and David J. Adams
P2Y purinoceptor activation mobilizes intracellular Ca2+ and induces a membrane current in rat intracardiac neurones, Dong-Mei Liu, Christopher Katnik, Mark R. Stafford, and David J. Adams
Tracer-toxins: cholera toxin B-saporin as a model, Ida J. Llewellyn-Smith, C L. Martin, Leonard F. Arnolda, and Jane B. Minson
Papers from 1999
The time course of haemodynamic, autonomic and skeletal muscle metabolic abnormalities following first extensive myocardial infarction in man, Stamatis Adamopoulos, G J. Kemp, Campbell H. Thompson, Leonard F. Arnolda, Franois Brunotte, John R. Stratton, George K. Radda, Bheeshma Rajagopalan, Dimitrios T. Kremastinos, and Andrew J. S Coats
Conotoxins and their potential pharmaceutical applications, David J. Adams, Paul F. Alewood, David J. Craik, Roger Drinkwater, and Richard J. Lewis
Activation of spinal opioid receptors contributes to hypotension after hemorrhage in conscious rats, Kooi K. Ang, Robert J. Mcritchie, Jane B. Minson, Ida J. Llewellyn-Smith, Paul Pilowsky, John Chalmers, and Leonard F. Arnolda
Animal models of heart failure, Leonard F. Arnolda, Ida J. Llewellyn-Smith, and Jane B. Minson
Monocular focal retinal lesions induce short-term topographic plasticity in adult cat visual cortex, Michael B. Calford, Leisa M. Schmid, and Marcello G.P Rosa
Single amino acid substitutions in α-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor, Ron C. Hogg, Les Miranda, David J. Craik, Richard J. Lewis, Paul F. Alewood, and David J. Adams
Mechanisms of verapamil inhibition of action potential firing in rat intracardiac ganglion neurons, Ron C. Hogg, C Trequattrini, L. Catacuzzeno, A Petris, F Franciolini, and David J. Adams
Retrogradely transported CTB-saporin kills sympathetic preganglionic neurons, Ida J. Llewellyn-Smith, C L. Martin, Leonard F. Arnolda, and Jane B. Minson
Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones, Amanda B. Smith and David J. Adams
Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia, Amanda B. Smith, Leonid Motin, N Lavidis, and David J. Adams
Neurokinin-1 receptors and spinal cord control of blood pressure in spontaneously hypertensive rats, Samuel G. Solomon, Ida J. Llewellyn-Smith, Jane B. Minson, Leonard F. Arnolda, John Chalmers, and Paul Pilowsky
Papers from 1998
Opioid receptor-mediated inhibition of ω-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons, David J. Adams and Carlo Trequattrini
Cutaneous vasoconstriction with alerting stimuli in rabbits reflects a patterned redistribution of cardiac output, W W. Blessing, Leonard F. Arnolda, and Y-H Yu
Short-term plasticity in adult somatosensory cortex, M B. Calford, J C. Clarey, and R Tweedale
Inhibition and inhibitory plasticity in the mammalian auditory midbrain, Mike B. Calford and Yuri Saalmann
ACh- and caffeine-induced Ca2+ mobilization and current activation in rabbit arterial endothelial cells, P Fransen, Christopher Katnik, and David J. Adams
Neuroplasticity and psychiatry, Bruce D. Gynther, Mike B. Calford, and Pankaj Sah
Ciguatoxin (CTX-1) modulates single tetrodotoxin-sensitive sodium channels in rat parasympathetic neurones, Ron C. Hogg, Richard J. Lewis, and David J. Adams
Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons, G Jeglitsch, K Rein, D G. Baden, and David J. Adams
Interhemispheric connections of somatosensory cortex in the flying fox, Leah Krubitzer, Janine C. Clarey, Rowan Tweedale, and Mike B. Calford
GABA- and glutamate-immunoreactive synapses on sympathetic preganglionic neurons projecting to the superior cervical ganglion, Ida J. Llewellyn-Smith, Leonard F. Arnolda, Paul Pilowsky, John Chalmers, and Jane B. Minson
α-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors, Marion L. Loughnan, Trudy Bond, Ann Atkins, Javier Cuevas, David J. Adams, Natalie M. Broxton, Bruce G. Livett, John G. Down, Alun Jones, Paul F. Alewood, and Richard J. Lewis
Low-dose diuretic and/or dietary sodium restriction when blood pressure is resistant to ACE inhibitor, Lindon M. H Wing, Leonard F. Arnolda, Paula J. Harvey, Jane Upton, Danielle Molloy, Genevieve M. Gabb, Alexandra J. C Bune, and John Chalmers
Papers from 1997
Essential hypertension, Leonard F. Arnolda, Ida J. Llewellyn-Smith, and Jane B. Minson
Central control mechanisms in hypertension, Leonard F. Arnolda, Hui H. Wang, Jane B. Minson, Ida J. Llewellyn-Smith, Satoshi Suzuki, Paul Pilowsky, and John Chalmers
M4 muscarinic receptor activation modulates calcium channel currents in rat intracardiac neurons, Javier Cuevas and David J. Adams
Passive and active membrane properties of isolated rat intracardiac neurons: Regulation by H- and M-currents, Javier Cuevas, Alexander A. Harper, C Trequattrini, and David J. Adams