The Illawarra Health and Medical Research Institute is a partnership between the University of Wollongong and the South Eastern Sydney Illawarra Area Health Service. IHMRI's research focuses on health and medical issues that are common in the Illawarra region and is aimed at improving the health and well being of the local community. IHMRI's goal is to foster research collaboration through the IHMRI Research Network, creating a centre of excellence and innovation that represents the focal point of health and medical research in this region.
Papers from 2008
Microsatellite markers in the endangered Australian northern corroboree frog, Pseudophryne pengilleyi (Anura: Myobatrachidae) and amplification in other Pseudophryne species, M J Morgan, Phillip G. Byrne, C M Hayes, and J S Keogh
ω-Conotoxin inhibition of excitatory synaptic transmission evoked by dorsal root stimulation in rat superficial dorsal horn, Leonid Motin and David J. Adams
Modulation of brain metabolism by very low concentrations of the commonly used drug delivery vehicle dimethyl sulfoxide (DMSO), F A Nasrallah, Brett Garner, Graham E Ball, and C Rae
Homocysteine or renal impairment: which is the real cardiovascular risk factor?, Kathleen Potter, Gaeme J. Hankey, Daniel J. Green, John W. W. Eikelboom, and Leonard F. Arnolda
The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis, Kathleen Potter, Gaeme J. Hankey, Daniel J. Green, John W. W. Eikelboom, Konrad Jamrozik, and Leonard F. Arnolda
Ultrasound settings significantly alter arterial lumen and wall thickness measurements, Kathleen Potter, Christopher Reed, Daniel J. Green, Gaeme J. Hankey, and Leonard F. Arnolda
Immunohistochemical assessment of cyclic guanosine monophosphate (cGMP) and soluble guanylate cyclase (sGC) within the rostral ventrolateral medulla, Kellysan Powers-Martin, Anna M. Barron, Clare H. Auckland, John K. Mccooke, Douglas J. McKitrick, Leonard F. Arnolda, and Jacqueline K. Phillips
Sensorimotor gating of schizophrenia patients is influenced by 5-HT2A receptor polymorphisms, Boris B. Quednow, Kai-Uwe Kuhn, Rainald Mossner, Sibylle G. Schwab, Anna Schuhmacher, Wolfgang Maier, and Michael Wagner
Association of PIP5K2A with schizophrenia: a study in an Indonesian family sample, Llewellyn Saggers-Gray, Heriani Heriani, Herlina Y. Handoko, Irmansyah Irmansyah, Agung A.A.A Kusumawardhani, Ika Widyawati, Nurmiati Amir, Martina W. Nasrun, Sibylle G. Schwab, and Dieter B. Wildenauer
Neuronally selective μ-conotoxins from Conus striatus utilize an α-helical motif to target mammalian sodium channels, Christina I. Schroeder, Jenny Ekberg, Katherine J. Nielsen, Denise Adams, Marion L. Loughnan, Linda Thomas, David J. Adams, Paul F. Alewood, and Richard J. Lewis
Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1, Friderike Schuetz, Sharad Kumar, Philip Poronnik, and David J. Adams
DNA sequence variants in the metabotropic glutamate receptor 3 and risk to schizophrenia: an association study, Sibylle G. Schwab, Christine Plummer, Margot Albus, Margitta Borrmann-Hassenbach, Bernard Lerer, Matyas Trixler, Wolfgang Maier, and Dieter B. Wildenauer
Research on causes for schizophrenia: are we close?, Sibylle G. Schwab and Dieter B. Wildenauer
Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia, Cynthia Shannon Weickert, A L Miranda-Angulo, Jenny Wong, W R Perlman, S E Ward, V Radhakrishna, R E Straub, D R Weinberger, and J E Kleinman
The His452Tyr variant of the gene encoding the 5-HT2A receptor is specifically associated with consolidation of episodic memory in humans, Michael Wagner, Anna Schuhmacher, Sibylle G. Schwab, Astrid W. Zobel, and Wolfgang Maier
Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis, Jenny Wong, C M Quinn, I C Gelissen, and A Brown
The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation, Jenny Wong, C M Quinn, I C Gelissen, W Jessup, and A Brown
OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages, D Yan, M I Mayranpaa, Jenny Wong, J Perttila, M Lehto, M Jauhiainen, P T Kovanen, C Enholm, A Brown, and V M Olkkonen
Kir and Kv channels regulate electrical properties and proliferation of adult neural precursor cells, Takahiro Yasuda, Perry F. Bartlett, and David J. Adams
Unipolar depression and hippocampal volume: impact of DNA sequence variants of the glucocorticoid receptor gene, Astrid W. Zobel, Frank Jessen, Olrik von Widdern, Anna Schuhmacher, Susanne Hofeis, Martin Metten, Marcella Rietschel, Lukas Scheef, Wolfgang Block, Tim Becker, Hans H. Schild, Wolfgang Maier, and Sibylle G. Schwab
Papers from 2007
Terrestrial toadlets use chemosignals to recognise conspecifics, locate mates and strategically adjust calling behaviour, Phillip G. Byrne and J Scott Keogh
The educational outcomes of young people 4-5 years after leaving care: an Australian perspective, Judy Cashmore, Marina Paxman, and Michelle Townsend
Chemical modification of conotoxins to improve stability and activity, David J. Craik and David J. Adams
NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity, Leanne M. Dibbens, Jenny Ekberg, I Taylor, B L. Hodgson, Sarah J. Conroy, I L. Lensink, Sharad Kumar, M A. Zielinski, L A. Harkin, G R. Sutherland, David J. Adams, S F. Berkovic, I E. Scheffer, J C. Mulley, and Philip Poronnik
Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by ubiquitination: novel role for Nedd4-2, Jenny Ekberg, Friderike Schuetz, Natasha A. Boase, Sarah J. Conroy, Jantina Manning, Sharad Kumar, Philip Poronnik, and David J. Adams
Apoptosis induces neuronal apolipoprotein-E synthesis and localization in apoptotic bodies, David A. Elliott, Woojin S. Kim, David A. Jans, and Brett Garner
Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration, Elias N. Glaros, Woojin S. Kim, Benjamin J. Wu, Cacang Suarna, Carmel M. Quinn, Kerry-Anne Rye, Roland Stocker, Wendy Jessup, and Brett Garner
Zinc supplementation inhibits lipid peroxidation and the development of atherosclerosis in rabbits fed a high cholesterol diet, Andrew M. Jenner, M Ren, Reshmi Rajendran, Pan Ning, B Huat, Frank Watt, and Barry Halliwell
Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics, Ai-Hua Jin, Hemma Brandstaetter, Simon T. Nevin, Chia Chia Tan, Richard J. Clark, David J. Adams, Paul F. Alewood, David J. Craik, and Norelle L. Daly
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-β peptide generation, Woojin Kim, Aldwin Rahmanto, Alvin Kamili, Kerry-Anne Rye, Gilles J. Guillemin, Ingrid C. Gelissen, Wendy Jessup, Andrew F. Hill, and Brett Garner
Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch, Anna Kloda, Linda Lua, Rhonda Hall, David J. Adams, and Boris Martinac
Polymodal regulation of NMDA receptor channels, Anna Kloda, Boris Martinac, and David J. Adams
Primary sensory neuron addition in the adult rat trigeminal ganglion: evidence for neural crest glio-neuronal precursor maturation, Alfonso Lagares, Hong-Yun Li, Xin-Fu Zhou, and Carlos Avendano
Isolation and structure-activity of μ-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels, Richard J. Lewis, Christina I. Schroeder, Jenny Ekberg, Katherine J. Nielsen, Marion L. Loughnan, Linda Thomas, Denise Adams, Roger Drinkwater, David J. Adams, and Paul F. Alewood
Isolation and characterization of neural crest progenitors from adult dorsal root ganglia, Hong-yun Li, Evonne Hwee Min Say, and Xin-Fu Zhou
Ablate and pace strategy for atrial fibrillation: long-term outcome of AIRCRAFT trial, Kang-Teng Lim, Michael J. E Davis, Anne Powell, Leonard F. Arnolda, Kath Moulden, Max Bulsara, and Rukshen Weerasooriya
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats, V Malik, Vasyl Holobotovskyy, Jacqueline K. Phillips, Douglas J. McKitrick, and Leonard F. Arnolda
ω-Conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels, Leonid Motin, Takahiro Yasuda, Christina I. Schroeder, Richard J. Lewis, and David J. Adams
Are α9α10 nicotinic acetylcholine receptors a pain target for α-conotoxins?, Simon T. Nevin, Richard J. Clark, Harry Klimis, MacDonald J. Christie, David J. Craik, and David J. Adams
Temporal relationship between renal cyst development, hypertension and cardiac hypertrophy in a new rat model of autosomal recessive polycystic kidney disease, Jacqueline K. Phillips, Deborah Hopwood, Rhonda A. Loxley, Kamaljit Ghatora, Jason Coombes, Ying Sin Tan, Joanne L. Harrison, Douglas J. McKitrick, Vasyl Holobotvskyy, Leonard F. Arnolda, and Gopala K. Rangan
Carotid intima-medial thickness measured on multiple ultrasound frames: evaluation of a DICOM-based software system, Kathleen Potter, Daniel J. Green, Christopher Reed, R J. Woodman, Gerald F. Watts, Brendan M. Mcquillan, V Burke, Gaeme J. Hankey, and Leonard F. Arnolda
Cellular distribution of the GABAA receptor-modulating 3α-hydroxy, 5α-reduced pregnane steroids in the adult rat brain, Y B. Saalmann, M T.K Kirkcaldie, S. Waldron, and M B. Calford
Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone, Mark R. Stafford, Perry F. Bartlett, and David J. Adams
Distinct activities of novel neurotoxins from Australian venomous snakes for nicotinic acetylcholine receptors, L St Pierre, H Fischer, David J. Adams, M Schenning, N Lavidis, John de Jersey, P P. Masci, and M F. Lavin
Educational outcomes of children on guardianship or custody orders: a pilot study, Michelle Townsend
The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells, Tara Walker, Takahiro Yasuda, David J. Adams, and Perry F. Bartlett
The identification of antioxidants in dark soy sauce, Huansong Wang, Andrew M. Jenner, Chung-Yung J. Lee, Guanghou Shui, Soon Yew Tang, Matthew Whiteman, Markus R. Wenk, and Barry Halliwell
Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol, Jenny Wong, Carmel M. Quinn, and Andrew J. Brown
Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis, Jenny Wong, Carmel M. Quinn, Gilles Guillemin, and Andrew J. Brown
Cortical reorganization consistent with spike timing but not correlation-dependent plasticity, Joshua M. Young, Wioletta J. Waleszczyk, Chun Wang, Michael B. Calford, Bogdan Dreher, and Klaus Obermayer
Roles of glial p75NTR in axonal regeneration, Xin-Fu Zhou and Hong-Yun Li
Papers from 2006
The legitimacy of my ethnographic gaze: context, methodology and insights from in the field, Lao PDR, K Alexander and D H R Spennemann
α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists, Christopher J. Armishaw, Norelle L. Daly, Simon T. Nevin, David J. Adams, David J. Craik, and Paul F. Alewood
Anti-tumour necrosis factor-alpha therapy over conventional therapy improves endothelial function in adults with rheumatoid arthritis, William Bilsborough, Helen Keen, Andrew Taylor, Gerard O'Driscoll, Leonard F. Arnolda, and Daniel J. Green
Evidence for adaptive male-mate choice in the fruit fly Drosophila melanogaster, Phillip G. Byrne and William R. Rice
Education and disadvantaged children, Judy Cashmore and Michelle Townsend
The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1, Richard J. Clark, Harald Fischer, Simon T. Nevin, David J. Adams, and David J. Craik
Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: A link between a key cell proliferative pathway and membrane synthesis, X Du, Ika Kristiana, Jenny Wong, and A Brown
Neuronal voltage-gated sodium channel subtypes: key roles in inflammatory and neuropathic pain, Jenny Ekberg and David J. Adams
μO-conotoxin MrVIB selectively blocks NaV1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits, Jenny Ekberg, A Jayamanne, Christopher W. Vaughan, S Aslan, Linda Thomas, Jorgen Mould, Roger Drinkwater, M D. Baker, B Abrahamsen, J N. Wood, David J. Adams, MacDonald J. Christie, and Richard J. Lewis
Investigation of the lipid component of neuromelanin, H Fedorow, R Pickford, E Kettle, M Cartwright, G Halliday, M Gerlach, P Riederer, and Brett Garner
Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury, Xin He, Andrew Jenner, Wei-Yi Ong, Akhlaq A. Farooqui, and Shutish C. Patel
HPLC analysis of discrete haptoglobin isoform N-linked oligosaccharides following 2D-PAGE isolation, Zhija He, L P. Aristoteli, L Kritharides, and Brett Garner
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells, Woojin Scott Kim, Gilles Guillemin, Elias N. Glaros, C K. Lim, and Brett Garner
Mutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine, Anna Kloda and David J. Adams
Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons, Chor Koh, Matthew Whiteman, Qiao-Xin Li, Barry Halliwell, Andrew Jenner, Boon Wong, Katrina Laughton, Markus Wenk, Colin Masters, Philip Beart, Ora Bernard, and Nam Cheung
Cautions in the use of biomarkers of oxidative damage; the vascular and antioxidant effects of dark soy sauce in humans, Chung-Yung Lee, Helen Isaac, Huansong Wang, Shan Huang, Lee-Hua Long, Andrew Jenner, Ronan Kelly, and Barry Halliwell
Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota, Hui Lee, Andrew Jenner, Chin S. Low, and Yuan K. Lee
Potential artifacts in the measurement of DNA deamination, Kok Lim, Shan Huang, Andrew Jenner, Huansong Wang, Soon Y. Tang, and Barry Halliwell
Quantitative gas chromatography mass spectrometric analysis of 2'-deoxyinosine in tissue DNA, Kok Lim, Andrew Jenner, and Barry Halliwell
Overcoming original antigenic sin to generate new CD8 T cell IFN-y responses in an antigen-experienced host, Xiaosong Liu, Graham R. Leggatt, Ian H. Frazer, Ranjeny Thomas, Joanne Dyer, Germain J P Fernando, and Jie Zhong
Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum, Marion L. Loughnan, Annette Nicke, Alun Jones, Christina I. Schroeder, Simon T. Nevin, David J. Adams, Paul F. Alewood, and Richard J. Lewis
Effects of training resumption on conduit arterial diameter in elite rowers, Louise H. Naylor, Gerard O'Driscoll, Martin Fitzsimons, Leonard F. Arnolda, and Daniel J. Green
Distinct subpopulations of cyclic guanosine monophosphate (cGMP) and neuronal nitric oxide synthase (nNOS) containing sympathetic preganglionic neurons in spontaneously hypertensive and Wistar-Kyoto rats, Kellysan Powers-Martin, Douglas J. McKitrick, Leonard F. Arnolda, and Jacqueline K. Phillips
NMDA receptor subunit-dependent modulation by conantokin-G and Ala(7)-conantokin-G, L Ragnarsson, Takahiro Yasuda, Richard J. Lewis, P R. Dodd, and David J. Adams
Zinc supplementation decreases the development of atherosclerosis in rabbits, Minqin Ren, Reshmi Rajendran, Pan Ning, Benny Kwong Huat, Ong Nam, Frank Watt, Andrew Jenner, and Barry Halliwell
Assessing sexual conflict in the Drosophila melanogaster laboratory model system, William R. Rice, Andrew D. Stewart, Edward H. Morrow, Jodell E. Linder, Nicole Orteiza, and Phillip G. Byrne
Neurosteroids involved in regulating inhibition in the inferior colliculus, Yuri B. Saalmann, Ian G. Morgan, and Mike B. Calford
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR, Jenny Wong, C M Quinn, and A Brown
Papers from 2005
Remating in Drosophila melanogaster: an examination of the trading-up and intrinsic male-quality hypotheses, Phillip G. Byrne and W R. Rice
Degree of adaptability of the somatosensory cortex to change: Prospects for integration of bone-mounted dental prostheses, Mike B. Calford
Neuroscience - Rewiring the adult brain, Mike Calford, Y Chino, A Das, U Eysel, C Gilbert, S Heinen, J Kaas, and S Ullman
Engineering stable peptide toxins by means of backbone cyclization: stabilization of the α-conotoxin MII, Richard J. Clark, Harald Fischer, Louise Dempster, Norelle L. Daly, K. . Johan Rosengren, Simon T. Nevin, Frederic A. Meunier, David J. Adams, and David J. Craik
Circulating surfactant protein-B levels increase acutely in response to exercise-induced left ventricular dysfunction, C G. De Pasquale, Leonard F. Arnolda, Ian R. Doyle, Phillip E. Aylward, Andrew E. Russell, and Andrew D. Bersten
Hypotension is associated with diuretic resistance in severe chronic heart failure, independent of renal function, C G. De Pasquale, J S. Dunne, R B. Minson, and Leonard F. Arnolda
Dolichol is the major lipid component of human substantia nigra neuromelanin, Heidi Fedorow, Russell Pickford, James M. Hook, Kay L. Double, Glenda M. Halliday, Manfred Gerlach, Peter Riederer, and Brett Garner
Developmental changes in expression of GABAA receptor-channels in rat intrinsic cardiac ganglion neurones, Harald Fischer, Alexander A. Harper, Colin R. Anderson, and David J. Adams
Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits, Harald Fischer, Dong-Mei Liu, Aven Lee, Janet C. Harries, and David J. Adams
Assessing the potential for an ongoing arms race within and between the sexes: selection and heritable variation, Urban Friberg, Timothy A. Lew, Phillip G. Byrne, and William R. Rice
Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-Phenyl-2-decanoylamino-3-morpholino-1- propanol is a novel cholesterol efflux accelerator, Elias N. Glaros, W B. Kim, C M Quinn, Jenny Wong, I C Gelissen, W Jessup, and Brett Garner
Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?, Barry Halliwell, J J Rafter, and Andrew M. Jenner
Human fecal water content of phenolics: The extent of colonic exposure to aromatic compounds, Andrew M. Jenner, J J Rafter, and Barry Halliwell
Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner, Refik Kanjhan, Elizabeth J. Coulson, David J. Adams, and Mark C. Bellingham
Human fecal water inhibits COX-2 in colonic HT-29 cells: Role of phenolic compounds, P C Karlsson, U Huss, Andrew M. Jenner, Barry Halliwell, L Bohlin, and J J Rafter
A consensus statement on osseoperception, I Klineberg, M B. Calford, B Dreher, P Henry, V Macefield, T Miles, M Rowe, B Sessle, and M Trulsson
Voltage-dependent inhibition of recombinant NMDA receptor-mediated currents by 5-hydroxytryptamine, Anna Kloda and David J. Adams
Oxidative damage in mitochondrial DNA is not extensive, Kok Seong Lim, Kandiah Jeyaseelan, Matthew Whiteman, Andrew M. Jenner, and Barry Halliwell
Ab initio and DFT cation affinity study of selected neurosteroids, Anthony A. Morrison, Mitchell C. Paul, Carl H. Parsons, Mike B. Calford, and Ellak I. von Nagy-Felsobuki
Reduced ventricular flow propagation velocity in elite athletes is augmented with the resumption of exercise training, Louise H. Naylor, Leonard F. Arnolda, Jenny A. Deague, David Playford, Antonio Maurogiovanni, Gerard O'Driscoll, and Daniel J. Green
A health impact assessment of an environmental management plan: the impacts on physical activity and social cohesion, Leonie Neville, Susan Furber, Sarah Thackway, Erica Gray, and Darren Mayne