Nanoparticles for super-resolution microscopy and single-molecule tracking

Authors

Dayong Jin, University of Technology SydneyFollow
Peng Xi, Peking University
Baoming Wang, University of Technology Sydney
Le Zhang, University of Technology Sydney
Jorg Enderlein, Gottingen University
Antoine M. van Oijen, University of WollongongFollow

RIS ID

128218

Publication Details

Jin, D., Xi, P., Wang, B., Zhang, L., Enderlein, J. & van Oijen, A. M. (2018). Nanoparticles for super-resolution microscopy and single-molecule tracking. Nature Methods, 15 415-423.

Abstract

We review the use of luminescent nanoparticles in super-resolution imaging and single-molecule tracking, and showcase novel approaches to super-resolution imaging that leverage the brightness, stability, and unique optical-switching properties of these nanoparticles. We also discuss the challenges associated with their use in biological systems, including intracellular delivery and molecular targeting. In doing so, we hope to provide practical guidance for biologists and continue to bridge the fields of super-resolution imaging and nanoparticle engineering to support their mutual advancement.

Grant Number

ARC/FL140100027