Concrete-filled steel tubular (CFT) columns are widely used as columns in many structural systems and a common failure mode of such tubular columns is inelastic outward local buckling near a column end. The use of fibre-reinforced polymer (FRP) jackets/wraps for the suppression of such local buckling has recently been proposed and has been proven to possess excellent potential in both retrofit/strengthening and new construction. This paper presents the results of an experimental study into the behaviour of large-scale FRP-confined CFT (CCFT) columns under combined axial compression and lateral loading. The test parameters included the stiffness of the FRP jacket and the loading scenario. The test results showed that the FRP jacket can effectively delay or even prevent outward local buckling at the end of a cantilevered CFT column, leading to significantly improved structural performance under combined constant axial compression and cyclic lateral loading. Compared to monotonic lateral loading, cyclic lateral loading was found to introduce more severe localized deformation near the column end and may lead to earlier FRP rupture within that region.